Protein Alignment ems and CDX2

DIOPT Version :9

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_011533177.1
• Gene: CDX2 / 1045
• HGNCID: 1806
• Length: 321
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 70/293 - (23%)
• Similarity: 102/293 - (34%)
• Gaps: 91/293 - (31%)

  Fly   194 PAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKP--AMMH------- 249
            |...:.||..|.......::..:::..|           ...|.|.|::|..  |.:.
Human    28 PQNFVSPPQYPDYGGYHVAAAAAAAANL-----------DSAQSPGPSWPAAYGAPLREDWNGYA 81

  Fly   250 PGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIAAA 314
            ||||.        .|.......:..|.|....|             .::|.:..|.|:||
Human    82 PGGAA--------AAANAVAHGLNGGSPAAAMG-------------YSSPADYHPHHHPH----- 120

  Fly   315 QFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYP---------WLLSRHGR 370
                      .|...||||.:.|:||........|.|.....:.||.|         |:
Human   121 ----------HHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWM------ 169

  Fly   371 IFPHRFP-----GS-FLVPP-----FRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQN 424
                |.|     || .|..|     .|...:.|..::..|.|:||..|..::|:....:..||..
Human   170 ----RKPAQQSLGSQALTSPSSTVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAAT 230

  Fly   425 LNLSETQVKVWFQNRRTKH-----KRMQQEDEK 452
            |.|||.|||:||||||.|.     |::||:.::
Human   231 LGLSERQVKIWFQNRRAKERKINKKKLQQQQQQ 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeobox	392..444	CDD:278475	23/56 (41%)
CDX2	XP_011533177.1	Caudal_act	13..171	CDD:282574	37/199 (19%)
		Homeobox	198..250	CDD:278475	23/51 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.900