Protein Alignment ems and Hoxb2

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_598793.2
• Gene: Hoxb2 / 103889
• MGIID: 96183
• Length: 354
• Species: Mus musculus
• Alignment Length: 287
• Identity: 76/287 - (26%)
• Similarity: 102/287 - (35%)
• Gaps: 102/287 - (35%)

  Fly   212 SSQPS------SSPTLL-------ISSPHATPPQQQQQQPPP---NYP----------KPAMMHP 250
            :||||      |.|.:|       |......||      |||   .:|          :|.....
Mouse    13 NSQPSLAECLTSFPAVLETFQTSSIKESTLIPP------PPPLEQTFPSLQLGASTLQRPGSQKQ 71

  Fly   251 GGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIAAAQ 315
            .|.||.:.  .||     |.|:.|..|..|..:                 |......|...||:.
Mouse    72 AGDGPALR--SPP-----PLPVAPPAPEFPWMK-----------------EKKSTKKPSQSAASP 112

  Fly   316 FQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSF 380
            ...|::::|..|..|    :...|||.....                               ||
Mouse   113 SPAASSVRASEVGSP----SDGPGLPECGGS-------------------------------GS- 141

  Fly   381 LVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKR 445
                    :|:|||::.:|||:||..|..|:|:....|..:|..|:|:|.||||||||||.||||
Mouse   142 --------RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 198

  Fly   446 MQQ--EDEKGGEGGSQRNMHNGSGDED 470
            ..|  |..:|..||.......|...|:
Mouse   199 QTQHREPPEGEPGGPSAQDDAGEPAEE 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	29/55 (53%)
Hoxb2	NP_598793.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..143		30/177 (17%)
		Antp-type hexapeptide	92..97		1/4 (25%)
		Homeodomain	142..198	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..231		12/33 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..295