Protein Alignment ems and nkx2-3

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_002937234.1
• Gene: nkx2-3 / 100486189
• XenbaseID: XB-GENE-852996
• Length: 328
• Species: Xenopus tropicalis
• Alignment Length: 229
• Identity: 62/229 - (27%)
• Similarity: 86/229 - (37%)
• Gaps: 82/229 - (35%)

  Fly   299 PPELPPQH------NPHLIAAAQ-----FQMAAALQA---------GHVLGPAAAAAAAAGLPPH 343
            ||...|||      ..|....||     ||.|:.:.|         |....|..:|..||  .||
 Frog    26 PPIAHPQHLQQQCSRAHPAHPAQDLDSDFQQASCMLAAGERCVYAGGEDKLPFLSAMGAA--EPH 88

  Fly   344 AAQFMPNPGMARDSYQLY--------------------PWLLSR----HGRI-FPHRFPGSFLVP 383
            .     :.|::.|.|...                    ...|::    .|:: .|.|       |
 Frog    89 G-----DVGLSPDRYVALRDPKEEDEEEEDSLREGGNKSCFLNKSPDGEGKLEDPDR-------P 141

  Fly   384 PFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQ 448
            ..|..::.|..||.:|:.:||..|:..:|:...||:.||.:|.|:.||||:||||||.|.||.:|
 Frog   142 KQRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLANSLKLTSTQVKIWFQNRRYKCKRQRQ 206

  Fly   449 E-----------------------DEKGGEGGSQ 459
            :                       |.|...||||
 Frog   207 DKSLEMGTHHPPPPRRVAVPVLVRDGKPCIGGSQ 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	25/55 (45%)
nkx2-3	XP_002937234.1	Homeodomain	147..203	CDD:459649	25/55 (45%)