Protein Alignment ems and nkx2-5

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001116891.1
• Gene: nkx2-5 / 100144646
• XenbaseID: XB-GENE-487966
• Length: 300
• Species: Xenopus tropicalis
• Alignment Length: 139
• Identity: 45/139 - (32%)
• Similarity: 58/139 - (41%)
• Gaps: 39/139 - (28%)

  Fly   349 PNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLV------------------------------- 382
            |.||....| :|...|..|.....|..|||||.|
 Frog    49 PYPGTPCLS-ELTEELAQRDSSKGPSPFPGSFFVKNYLEMDSSKDPKDDKKDICPLQKTLEHDKR 112

  Fly   383 -------PPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRR 440
                   |..||.::.|..||.:|:.:||..|:..:|:...||..||..|.|:.||||:||||||
 Frog   113 EAEDPERPRQRKRRKPRVLFSQAQVYELERRFKQQKYLSAPERDHLANVLKLTSTQVKIWFQNRR 177

  Fly   441 TKHKRMQQE 449
            .|.||.:|:
 Frog   178 YKCKRQRQD 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	25/55 (45%)
nkx2-5	NP_001116891.1	Homeodomain	132..182	CDD:459649	24/49 (49%)
		COG5576	<133..235	CDD:227863	26/54 (48%)