DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14362 and CIB2

DIOPT Version :10

Sequence 1:NP_650320.1 Gene:CG14362 / 41695 FlyBaseID:FBgn0038186 Length:206 Species:Drosophila melanogaster
Sequence 2:XP_005254183.1 Gene:CIB2 / 10518 HGNCID:24579 Length:210 Species:Homo sapiens


Alignment Length:253 Identity:57/253 - (22%)
Similarity:86/253 - (33%) Gaps:66/253 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   374 YTHPGYQMDDIIALIRWSLAVRRKCVIRAIPVATLSG--PTSGKN-YIDEWYEWARQIRRWTIGA 435
            |.|...||:     ..|..:|  :..:.|.|:....|  .||.|. ::....:..|...:.|:.|
Human   568 YHHEDRQMN-----TNWPASV--QVSVNATPLTIERGDNKTSHKPLHLKHVCQPGRNTIQITVTA 625

  Fly   436 AEVFHYFAIKFFRLPVTVSISFAAKFVFYYGFLL--------CIASI---YTLIAPIVTPAMLNA 489
            ....|.|.::....|...|:        ..|.|.        ||..|   ::.:|.......||.
Human   626 CCCSHLFVLQLVHRPSVRSV--------LQGLLKKRLLPAEHCITKIKRNFSSVAASSGNTTLNG 682

  Fly   490 VDHGVNGLVIP-NNKC---FMIIMFGFLG--LQYIWFFTVFLVNYL---CQ------PVFPRQTK 539
            .| ||....|. :.||   |..|.....|  .:::..|.  |.:||   |:      ||.     
Human   683 ED-GVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFD--LESYLQLNCERGTWRCPVC----- 739

  Fly   540 DKTGIIRNIFHWLMTWPTLIMYCCVELVAFLEVTVRGKSVCSHNASKKDNLVAPVPSK 597
            :||.::..:......|..|   ..::...|.|||:  ...||..         |||.|
Human   740 NKTALLEGLEVDQYMWGIL---NAIQHSEFEEVTI--DPTCSWR---------PVPIK 783

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14362NP_650320.1 EF-hand_7 114..182 CDD:463900
CIB2XP_005254183.1 EF-hand_7 107..173 CDD:463900
Blue background indicates that the domain is not in the aligned region.

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