Protein Alignment Nsf2 and DRC11

DIOPT Version :10

• Sequence 1: NP_788676.1
• Gene: Nsf2 / 41694
• FlyBaseID: FBgn0266464
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_001257514.1
• Gene: DRC11 / 79781
• HGNCID: 26195
• Length: 830
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 52/286 - (18%)
• Similarity: 97/286 - (33%)
• Gaps: 90/286 - (31%)

  Fly   258 VKGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVGESEANIRRLFAEAEEEEKRLG 322
            ||.:||.||.|.||.::...|.|...|....: :...|..||.|:
Human   576 VKSLLLAGPSGVGKKMLVHAICTETGANLFNL-SSSNIAGKYPGK-------------------- 619

  Fly   323 PNSGLHIIIFDEIDAICKARGSVAGNSGVHDTVVNQLLAKIDGVEQLN----------------- 370
              :||.:::........:.:.||.   .:.|| ......|:...|::|
Human   620 --NGLQMMLHAVFKVARQLQPSVV---WIEDT-EKTFYKKVPNAEKMNEPKRLKKHLPQILKLLK 678

  Fly   371 ---NILVIGMTNRRDMIDEALLRPGRLEVQ---------MEISLPNEQGRV----QILNIHTKRM 419
               .||::|.|.          ||...|:|         :.:..|:...|.    ||:.
Human   679 PDDRILIVGTTR----------RPFDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIE------ 727

  Fly   420 RDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMNRLIKADSKVHVDPEAMEKLRVTRAD 484
            |:...:.|.::.:.:|..|..|:...:..:|:...:....|     .::|..        :|..:
Human   728 RNGGVLTSALNVSCLAKVTDGFTQGHIVEVVKGVLTDQRIR-----RQIHKP--------LTAVE 779

  Fly   485 FLHALDNDIKPAFGAAQEMLENLLAR 510
            |:.|: ..:.|.:...:|..:|..|:
Human   780 FITAI-TSMNPVYKEEEESFKNWYAK 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_788676.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011
		RecA-like_NSF-SEC18_r1-like	224..400	CDD:410912	33/170 (19%)
		CDC48	<225..>611	CDD:273521	52/286 (18%)
DRC11	NP_001257514.1	RecA-like_IQCA1	551..710	CDD:410914	33/170 (19%)