DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nsf2 and pex1

DIOPT Version :9

Sequence 1:NP_001287318.1 Gene:Nsf2 / 41694 FlyBaseID:FBgn0266464 Length:752 Species:Drosophila melanogaster
Sequence 2:NP_001164306.1 Gene:pex1 / 793906 ZFINID:ZDB-GENE-070530-1 Length:1237 Species:Danio rerio


Alignment Length:474 Identity:128/474 - (27%)
Similarity:204/474 - (43%) Gaps:119/474 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 SIEKAHRMRAIKCPTDELSLTNKAI-VNVSDFTEEVKYVDISPGPGLHYIFALEKISGPELPLGH 65
            ::.:.|..:::|...||:.|.:..| :.|:..||...:..::...|.|:..:..||..|:     
Zfish   646 AVLRQHISQSLKDLVDEIVLRSSLIALIVTAQTEHALHPTLTVVQGSHFFQSFCKIPTPD----- 705

  Fly    66 VGFSLVQRKWATLSINQEIDVRPYRFDASADIITLVSFETDFLQKKTTTQEPYDSDEMAKEFLMQ 130
                                 :..|.:....:|...||:        ..|...|.|.:|||    
Zfish   706 ---------------------QAQRVEILKSLIVKKSFQ--------VCQTTLDLDSVAKE---- 737

  Fly   131 FAGMPLTVGQTLVFQFKDKKFL---GLAVKTLEAVDPRTVGDSLPKTRNVRFGRILGNTVVQFEK 192
                  |.|    |..:|...|   .:...||...:..:..|                    |.:
Zfish   738 ------TEG----FMARDLNLLLERAIHANTLHNSEDLSCKD--------------------FRQ 772

  Fly   193 AENSVLNLQGRSKGKIVRQSIINPDWD--------FGKMGIGGLDKEFNAIFRRAFASRVFPPEL 249
            |      |||.:...:         ||        .|...||||.:....:.........: |.|
Zfish   773 A------LQGFTPPSL---------WDAQLQAPSGAGMERIGGLHEARQLLMDIILLPAKY-PLL 821

  Fly   250 VEQLGIKHVKGILLYGPPGTGKTLMARQIGTMLNAREPKI----VNGPQILDKYVGESEANIRRL 310
            ...|.::...|:||||.|||||||:|..:     |:|..:    :.||::|.||:|.||..:|.:
Zfish   822 FSSLPLRQCSGVLLYGAPGTGKTLLAGAV-----AKESGMNFISIKGPELLSKYIGASEQAVRDV 881

  Fly   311 FAEAEEEEKRLGPNSGLHIIIFDEIDAICKARGSVAGNSGVHDTVVNQLLAKIDGVEQLNNILVI 375
            |..|::.:.        .|:.|||.|::...||.  .|:||.|.||||||.::||||.|..:.|:
Zfish   882 FQRAQQAKP--------CILFFDEFDSLAPRRGH--DNTGVTDRVVNQLLTQLDGVEGLTGVYVL 936

  Fly   376 GMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHTKRMRDFNKIASDVDNNEIAAKTKN 440
            ..::|.|:||.||||||||:..:....|:.:.|::||...|..:    .:|:|||.::||..|:.
Zfish   937 AASSRPDLIDPALLRPGRLDKSLYCPPPDREARLEILRALTHSV----PLAADVDLDQIAGATEL 997

  Fly   441 FSGAELEGLVRAAQSTAMN 459
            |:||:|:.|:..||..|::
Zfish   998 FTGADLKALLYNAQLEAIH 1016

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nsf2NP_001287318.1 CDC48_N 9..89 CDD:215012 13/80 (16%)
CDC48_2 117..>170 CDD:215011 12/55 (22%)
AAA 259..404 CDD:214640 61/148 (41%)
AAA 261..402 CDD:278434 60/144 (42%)
AAA 543..674 CDD:214640
P-loop_NTPase 544..>613 CDD:304359
pex1NP_001164306.1 PEX-2N 12..89 CDD:286362
PEX-1N 101..171 CDD:286361
SpoVK 559..1026 CDD:223540 128/474 (27%)
P-loop_NTPase 559..686 CDD:304359 9/39 (23%)
AAA 833..962 CDD:278434 60/143 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.000

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