DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsf2 and pex1

DIOPT Version :9

Sequence 1:	NP_001287318.1	Gene:	Nsf2 / 41694	FlyBaseID:	FBgn0266464	Length:	752	Species:	Drosophila melanogaster
Sequence 2:	XP_004915478.1	Gene:	pex1 / 779516	XenbaseID:	XB-GENE-985415	Length:	1269	Species:	Xenopus tropicalis

Alignment Length:	324	Identity:	107/324 - (33%)
Similarity:	167/324 - (51%)	Gaps:	36/324 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 LVFQFKDKKFLGLAVKTLEAVDPRTVGDSLPKTRNVRFGRILGNTVVQFEKAEN--SVLNLQGRS 204
            |.||:..::..|...:....:..|.:..|:.|.:..|...::.:| ..|::|..  :.|:|:...
Frog   760 LDFQYLARETEGFVARDFTMLVERAIESSVSKRQICRIEDLVLST-TDFQRALKGFTPLSLRNAQ 823

  Fly   205 KGKIVRQSIINPDWDFGKMGIGGLDKEFNAIFRRAFASRVFPPELVEQLGIKHVKGILLYGPPGT 269
            ..|..:|     ||:.    :||| .:...:.:.........|||...|.|:|..|:||||.|||
Frog   824 LHKPKKQ-----DWNM----VGGL-HDIRQVLKDTIELPAKYPELFANLPIRHRSGVLLYGAPGT 878

  Fly   270 GKTLMARQIGTMLNAREPKI----VNGPQILDKYVGESEANIRRLFAEAEEEEKRLGPNSGLHII 330
            ||||:|..|     |.|.::    :.||::|.||:|.||..:|.:|..|:..:.        .|:
Frog   879 GKTLLAGVI-----AHESRMNFISIKGPELLSKYIGASEQAVRDVFTRAQAAKP--------CIL 930

  Fly   331 IFDEIDAICKARGSVAGNSGVHDTVVNQLLAKIDGVEQLNNILVIGMTNRRDMIDEALLRPGRLE 395
            .|||.|:|...||.  .|:||.|.||||:|.::||||.|..:.|:..|:|.|:||.||||||||:
Frog   931 FFDEFDSIAPRRGH--DNTGVTDRVVNQMLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLD 993

  Fly   396 VQMEISLPNEQGRVQILNIHTKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMN 459
            ..:....|::..|.:||    |.:.....:..:||...||:.|..|:||:|:.|:..||..|::
Frog   994 ECLYCPPPDQDSRFEIL----KGLSHSMLLDENVDLKHIASLTDYFTGADLKALLYNAQLEAIH 1053

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011	5/27 (19%)
		AAA	259..404	CDD:214640	63/148 (43%)
		AAA	261..402	CDD:278434	62/144 (43%)
		AAA	543..674	CDD:214640
		P-loop_NTPase	544..>613	CDD:304359
pex1	XP_004915478.1	PEX-2N	11..93	CDD:370393
		PEX-1N	99..174	CDD:370392
		CDC48	<587..1052	CDD:273521	106/321 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910