Protein Alignment Nsf2 and spata5l1

DIOPT Version :9

• Sequence 1: NP_001287318.1
• Gene: Nsf2 / 41694
• FlyBaseID: FBgn0266464
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_001070056.2
• Gene: spata5l1 / 767648
• ZFINID: ZDB-GENE-060929-204
• Length: 748
• Species: Danio rerio
• Alignment Length: 564
• Identity: 155/564 - (27%)
• Similarity: 237/564 - (42%)
• Gaps: 125/564 - (22%)

  Fly   225 IGGLDKEFNAIFRRAFASRVFP---PELVEQLGIKHVKGILLYGPPGTGKTLM----ARQIGTML 282
            :||::..|.::....    .||   |..:.|||:...:|:||.||||.||||:    |:.||..|
Zfish   189 LGGMEDVFASLKEMI----TFPLRYPGSLRQLGLSCPRGLLLIGPPGVGKTLLVRCVAKDIGATL 249

  Fly   283 NAREPKIVNGPQILDKYVGESEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKARGSVAG 347
                 ..||||::.....||||.|:||:|     |:.|...:.|..:::.||||::|..|  ...
Zfish   250 -----VTVNGPEVTGSRPGESEENLRRVF-----EQARDAADDGPCVLLIDEIDSLCPRR--TGS 302

  Fly   348 NSGVHDTVVNQLLAKIDGVEQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQIL 412
            :|...:.:|.|||..:|.:......::||.||:.|.:|.||.||||.:.::.|.:|:...|..||
Zfish   303 SSAPENRLVAQLLTLMDAIGSHEGFVIIGATNQPDSLDPALRRPGRFDREVIIGVPSLLQRRSIL 367

  Fly   413 NIHTKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMNRLIKADSKVHVDPEAMEK 477
            ....:.|    .::.|||.|.:|..|..:.||:|..|.|.|...||.         |....|.|.
Zfish   368 KCVCREM----PLSPDVDLNTLAEMTCGYVGADLSALSREAALQAMR---------HSQMGASEP 419

  Fly   478 LRVTRADFLHALDN-------------DIKPAFGAAQEMLENLLARGIINW----GPPVTELLED 525
              |:...|:.||.:             |.||                 |.|    |      |||
Zfish   420 --VSMQHFMQALRHVQPSCLRSSIGATDFKP-----------------IGWEQIGG------LED 459

  Fly   526 GMLSVQQA--------KATESSGLV---SVLIEGAPNSGKSALAANLAQLSDFPFVKVCSPE--- 576
            ..|.::|:        :|....|:.   .||:.|.|...|:.|....|..|...|..:...|
Zfish   460 VKLKLKQSIEWPMRFPEAFVRLGVSRPRGVLLYGPPGCAKTTLVKAAASSSHCSFFSLSGAELFS 524

  Fly   577 DMVGFTESAKCLHIRKIFDDAYRSTLSCIVVDNVERLLDYGPIGPRYS-NLTLQALLVLLKKQPP 640
            ..||.:|..    :.::|..|.....|.:.:|.|:.::.....|...| ::..|.|.|||.:...
Zfish   525 PYVGDSEKT----LAQLFAQARACAPSIVFLDEVDSMVGSREDGSSSSHSVQSQVLSVLLTELDG 585

  Fly   641 KG----------RKLLILCTSSRRDV-LEEMEMLSAFT-SVLHVSNLSTPENVLAVLDDSDLFSP 693
            .|          ||:.:|....:.|| |.:||:..... .||.|:..:.||.:     ||.|..|
Zfish   586 VGVRTLERRSTCRKIALLEGGDQEDVRLHQMELQEVCNKDVLIVAATNRPEAL-----DSALLRP 645

  Fly   694 EELQSI--------ARKMAGKRLC---IGIKKLLALIDMIRQSE 726
            ..|..|        ..::|..|:|   :.:.:.:.|.|:..|:|
Zfish   646 GRLDQIIYVPPPDLQARLAVLRICTKSVPLHQDVCLEDLAAQTE 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011
		AAA	259..404	CDD:214640	55/148 (37%)
		AAA	261..402	CDD:278434	54/144 (38%)
		AAA	543..674	CDD:214640	37/146 (25%)
		P-loop_NTPase	544..>613	CDD:304359	18/71 (25%)
spata5l1	NP_001070056.2	CDC48	13..740	CDD:273521	155/564 (27%)
		AAA	224..357	CDD:278434	54/144 (38%)
		AAA	489..655	CDD:278434	45/174 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900