Protein Alignment Nsf2 and Spata5l1

DIOPT Version :9

• Sequence 1: NP_001287318.1
• Gene: Nsf2 / 41694
• FlyBaseID: FBgn0266464
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_001103117.1
• Gene: Spata5l1 / 691729
• RGDID: 1595990
• Length: 747
• Species: Rattus norvegicus
• Alignment Length: 593
• Identity: 146/593 - (24%)
• Similarity: 247/593 - (41%)
• Gaps: 136/593 - (22%)

  Fly   221 GKMGIGGLDKEFNAIFRRAFASRVFPPELVEQLGIKHVKGILLYGPPGTGKTLMARQIGTMLNAR 285
            |::.:|||.:..::: |......:..|..:..||:...:|:||.||||.|||.:.|.:.....|
  Rat   191 GEVTLGGLSETADSL-RELLRLPLCYPLALAALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGA- 253

  Fly   286 EPKIVNGPQILDKYVGESEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKARGSVAGNSG 350
            |...|:.|.:.....||:|.|:||:|..|:|...| ||:    ::..||:||:|..||  .....
  Rat   254 ELLAVSAPALQGTRPGETEENVRRVFQRAQELASR-GPS----LLFLDEVDALCPRRG--GPQRA 311

  Fly   351 VHDTVVNQLLAKIDGVEQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIH 415
            ....||.|:|..:||:.....::|:|.|||.|.:|.||.||||.:.::.|..|..:.|..||.:.
  Rat   312 PESRVVAQVLTLLDGIHGDREVVVVGATNRPDELDPALRRPGRFDREVIIGTPTLKQREAILGVI 376

  Fly   416 TKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMNRLIKADSKVHVDPEAMEKLRV 480
            |.:|    .|:|.:|...:|..|..:.||:|..|.|.|.:.|   |:| :.|...:|      ::
  Rat   377 TSKM----PISSHIDLGLLAEMTVGYVGADLTALCREAATCA---LLK-NEKNQNNP------KI 427

  Fly   481 TRADFLHALD-------------NDIKPA----FGAAQEMLENLLARGIINWGPPVTELLEDGML 528
            ...|||.|..             .||:|.    .|..:::  .|..:..:.|  |:....|...:
  Rat   428 EETDFLEAFKKVQPSSFRSSIGLTDIRPVGWEQIGGLEDV--KLKLKQCVEW--PLKFPQEFARM 488

  Fly   529 SVQQAKATESSGLVSVLIEGAPNSGKSALAANLAQLSDFPFVKVCSPE---DMVGFTESAKCLHI 590
            .:.|.|        .:|:.|.|...|:.|...||......||.||..:   ..||.:|..    :
  Rat   489 GLTQPK--------GLLLYGPPGCAKTTLVRALATSCHCSFVSVCGADLFSPFVGDSEKV----L 541

  Fly   591 RKIFDDAYRSTLSCIVVDNVERLLDYGPIGPRYSNLTLQALLVLLKK------------------ 637
            .::|..|..:|.:.:.:|.::.:|....:|....:...:.|.|||.:
  Rat   542 SQVFRQARANTPALVFLDEIDSVLGSRSVGSSGCDARERVLSVLLNELDGVGVRTVERRGSKASQ 606

  Fly   638 ---QPPKGRKLLILCTSSRRDVLEE----------------------MEMLSAFTSVLHVSNLST 677
               |....|.::|:..::|.|||::                      :.:|...|:.:.:....:
  Rat   607 QECQEILSRSVMIVVATNRPDVLDDALLRPGRLDKMVYVPPPDREGRLSILKVCTNNMPIGLNVS 671

  Fly   678 PENVLAVLDDSDLFSPEELQSIARKMAGKRLCIGIKKLLALIDMIRQSEPHQRVIKFLSKMEEEG 742
            .||:.|   ::..||..:|:::.::.|          |.||                     :|.
  Rat   672 LENLAA---ETCYFSGADLRNLCKEAA----------LFAL---------------------QEN 702

  Fly   743 GLEMDRVQ 750
            |||...|:
  Rat   703 GLEATTVE 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011
		AAA	259..404	CDD:214640	54/144 (38%)
		AAA	261..402	CDD:278434	53/140 (38%)
		AAA	543..674	CDD:214640	33/176 (19%)
		P-loop_NTPase	544..>613	CDD:304359	18/71 (25%)
Spata5l1	NP_001103117.1	CDC48	14..738	CDD:273521	146/593 (25%)
		AAA	230..362	CDD:278434	52/139 (37%)
		AAA	496..646	CDD:278434	31/153 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900