DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsf2 and Fignl2

DIOPT Version :9

Sequence 1:	NP_001287318.1	Gene:	Nsf2 / 41694	FlyBaseID:	FBgn0266464	Length:	752	Species:	Drosophila melanogaster
Sequence 2:	NP_001201840.1	Gene:	Fignl2 / 668225	MGIID:	3646919	Length:	644	Species:	Mus musculus

Alignment Length:	202	Identity:	57/202 - (28%)
Similarity:	93/202 - (46%)	Gaps:	29/202 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   261 ILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVGESEANIRRLFAEAEEEEKRLGPNS 325
            :|.:||.|.||.|:.|.:.|.|.|...:: .|..:......|....::..||.|     |..|.:
Mouse   423 VLFFGPRGCGKALLGRCLATRLGATLLRL-RGAGLAASGAVEGARLLQAAFAAA-----RCRPPA 481

  Fly   326 GLHIIIFDEIDAICKARGSVAGNSGVHDTVVNQLLAKIDGV--EQLNNILVIGMTNRRDMIDEAL 388
               :::..|:||:..||...|       ::...||..:||.  .:.:.:||:|.|:|...:|||.
Mouse   482 ---VLLISELDALLPARDDGA-------SLRAPLLTCLDGSCGARADGVLVVGTTSRPAALDEAT 536

  Fly   389 LRPGRLEVQMEISLPNEQGRVQILNIHTKRMRDFNKIASDVDNNEIAA---KTKNFSGAELEGLV 450
            .|  |..::..::||:...|.|||      .|...:....::..|:||   .|:.|||.||..|.
Mouse   537 RR--RFALRFYVALPDGAARGQIL------QRALAQQGCALNERELAALVQGTQGFSGGELGQLC 593

  Fly   451 RAAQSTA 457
            :.|.:.|
Mouse   594 QQAAAEA 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011
		AAA	259..404	CDD:214640	39/144 (27%)
		AAA	261..402	CDD:278434	38/142 (27%)
		AAA	543..674	CDD:214640
		P-loop_NTPase	544..>613	CDD:304359
Fignl2	NP_001201840.1	SpoVK	<381..638	CDD:223540	57/202 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900