Protein Alignment Nsf2 and Spata5

DIOPT Version :9

• Sequence 1: NP_001287318.1
• Gene: Nsf2 / 41694
• FlyBaseID: FBgn0266464
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_001156983.1
• Gene: Spata5 / 57815
• MGIID: 1927170
• Length: 893
• Species: Mus musculus
• Alignment Length: 575
• Identity: 161/575 - (28%)
• Similarity: 263/575 - (45%)
• Gaps: 94/575 - (16%)

  Fly   225 IGGLDKEFNAIFRRAFASRVFPPELVEQLGIKHVKGILLYGPPGTGKTLMARQIGTMLNAREPKI 289
            ||||:.:..|| |......:..|||.:..||...:|:|||||||||||::||.:...:.| ...:
Mouse   355 IGGLNSQLKAI-REIIELPLKQPELFKSYGIPAPRGLLLYGPPGTGKTMIARAVANEVGA-YVSV 417

  Fly   290 VNGPQILDKYVGESEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKARGSVAGNSGVHDT 354
            :|||:|:.|:.||:||.:|::||||....    |:    ||..||:||:|..|  ....|.|...
Mouse   418 INGPEIISKFYGETEARLRQIFAEATLRH----PS----IIFIDELDALCPKR--EGAQSEVEKR 472

  Fly   355 VVNQLLAKIDGVEQLNN---ILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHT 416
            ||..||..:||:....:   :||:|.|||...:|.||.||||.:.::||.:||.|.|:.||.
Mouse   473 VVASLLTLMDGIGSEGSEGRVLVLGATNRPQALDAALRRPGRFDKEIEIGIPNAQDRLDILQ--- 534

  Fly   417 KRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMNRLIK-----ADSKVHVDPEAME 476
            |.:|....:.:..:...:|.....:.||:|:.|...|...|:.|:::     .||||      ..
Mouse   535 KLLRRVPHLLTKAELLRLANNAHGYVGADLKALCNEAGLHALRRVLRKQPNLPDSKV------AG 593

  Fly   477 KLRVTRADFLHALDNDIKPAFGAAQEM--------------LEN--LLARGIINWGPPVTELLED 525
            .:::|..|||..: |||:|:  |.:|:              |||  |..:..:.|  |:......
Mouse   594 MVKITLNDFLQGM-NDIRPS--AMREVAIDVPNVSWSDIGGLENIKLKLKQAVEW--PLKHPKSF 653

  Fly   526 GMLSVQQAKATESSGLVSVLIEGAPNSGKSALAANLAQLSDFPFVKVCSPEDM---VGFTESAKC 587
            ..:.:|..|        .||:.|.|...|:.:|..||..|...|:.:..||.|   ||.:|.|
Mouse   654 NRMGIQPPK--------GVLLYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERA-- 708

  Fly   588 LHIRKIFDDAYRSTLSCIVVDNVERLLDYGPIGPRYSNLTLQALLVLLKKQP--PKGRKLLILCT 650
              :|:||..|.....|.|..|.::.|...........|:..:.|..||.:..  .:.:.:.:|..
Mouse   709 --VREIFRKARAVAPSIIFFDELDALAVERGSSSGAGNVADRVLAQLLTEMDGIEQLKNVTVLAA 771

  Fly   651 SSRRDVLEEMEM---------------LSAFTSVLHVSNLSTPENVLAVLDD----SDLFSPEEL 696
            ::|.|.:::..|               .:....:|::...|.|.:....||:    :|.:|..|:
Mouse   772 TNRPDRIDKALMRPGRIDRIIYVPLPDAATRREILNLQFHSMPISNEVDLDELVLQTDTYSGAEI 836

  Fly   697 QSIARKMAGKRL-------CIGIKKLLALIDMIRQSEPHQRVIKFLSKMEEEGGL 744
            .::.::.|...|       ||..:.....:.::....| :.:.:|....:|:.||
Mouse   837 IAVCKEAALLALEENIKADCIMKRHFTQALSIVTPRIP-ESLRRFYEDYQEKSGL 890

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011
		AAA	259..404	CDD:214640	61/147 (41%)
		AAA	261..402	CDD:278434	60/143 (42%)
		AAA	543..674	CDD:214640	34/150 (23%)
		P-loop_NTPase	544..>613	CDD:304359	24/71 (34%)
Spata5	NP_001156983.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38
		CDC48_N	64..132	CDD:304500
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..227
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	239..315
		SpoVK	370..882	CDD:223540	151/549 (28%)
		AAA	390..522	CDD:278434	59/142 (42%)
		AAA	664..796	CDD:278434	33/135 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810