Protein Alignment Nsf2 and nsfb

DIOPT Version :10

• Sequence 1: NP_788676.1
• Gene: Nsf2 / 41694
• FlyBaseID: FBgn0266464
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_001019625.3
• Gene: nsfb / 554200
• ZFINID: ZDB-GENE-050808-1
• Length: 747
• Species: Danio rerio
• Alignment Length: 743
• Identity: 443/743 - (59%)
• Similarity: 570/743 - (76%)
• Gaps: 6/743 - (0%)

  Fly     8 RMRAIKCPTDELSLTNKAIVNVSDFTEEVKYVDISPGPGLHYIFALEKISGPELPLGHVGFSLVQ 72
            :|:|.:||||||||||..:.:..|| :..:::.|...|...::|.:.  :.|.:..|.:.|||.|
Zfish     5 QMQAARCPTDELSLTNCVVASEKDF-KSGQHLTIKTTPTQKFVFTVR--THPSVVPGTIAFSLPQ 66

  Fly    73 RKWATLSINQEIDVRPYRFDASADIITLVSFETDFLQKKTTTQEPYDSDEMAKEFLMQFAGMPLT 137
            ||||.||:||:::|..|.||.|...:..::.|.||||||:....|||||:||.||:..|.....:
Zfish    67 RKWAGLSLNQDVEVSVYNFDPSRQYVGTMTIEIDFLQKKSIDSNPYDSDKMAIEFIQCFTAQAFS 131

  Fly   138 VGQTLVFQFKDKKFLGLAVKTLEAVDPRTV-GD-SLPKTRNVRFGRILGNTVVQFEKAENSVLNL 200
            :.|..||.|.||.| .|.:|.:||:||..: |: :..|...:..|.:.||:.|.|||.|:|.:||
Zfish   132 MSQQFVFSFCDKLF-ALVIKDIEAMDPSILRGEQNSSKKHKIDIGLLHGNSQVIFEKVESSSVNL 195

  Fly   201 QGRSKGKIVRQSIINPDWDFGKMGIGGLDKEFNAIFRRAFASRVFPPELVEQLGIKHVKGILLYG 265
            .|::|.|..|||||||||:|.:||||||||||:.|||||||||||||::|||:|.||||||||||
Zfish   196 IGKAKTKGSRQSIINPDWNFERMGIGGLDKEFSDIFRRAFASRVFPPDIVEQMGCKHVKGILLYG 260

  Fly   266 PPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVGESEANIRRLFAEAEEEEKRLGPNSGLHII 330
            |||.||||||||||.||||||||:||||:||:|||||||||||:|||:||||:||||.|||||||
Zfish   261 PPGCGKTLMARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQKRLGANSGLHII 325

  Fly   331 IFDEIDAICKARGSVAGNSGVHDTVVNQLLAKIDGVEQLNNILVIGMTNRRDMIDEALLRPGRLE 395
            ||||||||||.|||:||::|||||||||||:|||||||||||||||||||.|:||||||||||||
Zfish   326 IFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLE 390

  Fly   396 VQMEISLPNEQGRVQILNIHTKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMNR 460
            |:|||.||:|.||||||||||.:|:..|.:|.|||..|:|.:|||:|||||||||||||||||||
Zfish   391 VKMEIGLPDETGRVQILNIHTAKMKQSNMLAKDVDVKELAVETKNYSGAELEGLVRAAQSTAMNR 455

  Fly   461 LIKADSKVHVDPEAMEKLRVTRADFLHALDNDIKPAFGAAQEMLENLLARGIINWGPPVTELLED 525
            .|||.::|.||.|..:.|:|:|:|||.:|:||||||||:.||...:.:..||:.|...|:::|.|
Zfish   456 HIKATTQVEVDTEKAQTLQVSRSDFLASLNNDIKPAFGSNQEDYSSYIMNGIVKWSNAVSDILGD 520

  Fly   526 GMLSVQQAKATESSGLVSVLIEGAPNSGKSALAANLAQLSDFPFVKVCSPEDMVGFTESAKCLHI 590
            |.|.|||.|.:|.:.||:||:||..:|||:||||.:|:.|.|||:|:|||:.|:||||:|||..|
Zfish   521 GELLVQQTKNSERTPLVTVLLEGPAHSGKTALAAKIAEQSQFPFIKICSPDKMIGFTETAKCQAI 585

  Fly   591 RKIFDDAYRSTLSCIVVDNVERLLDYGPIGPRYSNLTLQALLVLLKKQPPKGRKLLILCTSSRRD 655
            :|||:|||:|.|||:|||::|||||:.|||||:|||.||||||||||.||:|||||||.|:||:|
Zfish   586 KKIFEDAYKSQLSCVVVDDIERLLDFVPIGPRFSNLVLQALLVLLKKPPPRGRKLLILGTTSRKD 650

  Fly   656 VLEEMEMLSAFTSVLHVSNLSTPENVLAVLDDSDLFSPEELQSIARKMAGKRLCIGIKKLLALID 720
            ||:||.|..:|::.:|:.|:||.|:::..|:....|..||..:|.:::.|:.:.:|||||..||:
Zfish   651 VLQEMGMSDSFSTTIHIPNISTGEHLMEALELLGGFQEEERANIGKQVKGQSVWLGIKKLQMLIE 715

  Fly   721 MIRQSEPHQRVIKFLSKMEEEGGLEMDR 748
            |..|.....||.|||:.::|||.|..|:
Zfish   716 MSLQMPLEYRVQKFLALLKEEGALGSDK 743

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_788676.1	CDC48_N	9..89	CDD:215012	32/79 (41%)
		CDC48_2	117..>170	CDD:215011	24/54 (44%)
		RecA-like_NSF-SEC18_r1-like	224..400	CDD:410912	152/175 (87%)
		CDC48	<225..>611	CDD:273521	277/385 (72%)
nsfb	NP_001019625.3	None