DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsf2 and Pex1

DIOPT Version :9

Sequence 1:	NP_001287318.1	Gene:	Nsf2 / 41694	FlyBaseID:	FBgn0266464	Length:	752	Species:	Drosophila melanogaster
Sequence 2:	NP_652016.1	Gene:	Pex1 / 45460	FlyBaseID:	FBgn0013563	Length:	1006	Species:	Drosophila melanogaster

Alignment Length:	249	Identity:	85/249 - (34%)
Similarity:	132/249 - (53%)	Gaps:	34/249 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 PELVEQLGIKHVKGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVGESEANIRRLF 311
            |.:.....:::..|:|||||||||||.:..|:.|..|.|... |.||::|.||:|:||.|:|.||
  Fly   743 PTIFNASPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIIS-VKGPELLAKYIGQSEENVRNLF 806

  Fly   312 AEAEEEEKRLGPNSGLHIIIFDEIDAICKARGSVAGNSGVHDTVVNQLLAKIDGVEQLNNILVIG 376
            ..|.....        .::.|||.|::...||.  .::||.|.||||||.::||||.|..:.||.
  Fly   807 NRARSARP--------CVLFFDEFDSLAPKRGH--DSTGVTDRVVNQLLTELDGVEGLQGVTVIA 861

  Fly   377 MTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHTKRMRDFNKIASD------VDNNEIA 435
            .|:|.:::|.||||.||::..:|..||:...||:|          |..::|.      ||.:..|
  Fly   862 ATSRPELLDPALLRSGRIDRLVECPLPDAPARVRI----------FEALSSTLSLDECVDFDWFA 916

  Fly   436 AKTKNFSGAELEGLVRAAQSTAMNRLI------KADSKVHV-DPEAMEKLRVTR 482
            .||.|::||:::.::.:|...|:...:      |...|:.: ....:|..:.||
  Fly   917 GKTANYTGADIQSILTSANMAAVKEALAQFGHEKLAKKISLKQKHLIESFQTTR 970

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011
		AAA	259..404	CDD:214640	63/144 (44%)
		AAA	261..402	CDD:278434	61/140 (44%)
		AAA	543..674	CDD:214640
		P-loop_NTPase	544..>613	CDD:304359
Pex1	NP_652016.1	PEX-1N	93..168	CDD:286361
		SpoVK	479..974	CDD:223540	85/249 (34%)
		P-loop_NTPase	480..604	CDD:304359
		AAA	757..887	CDD:278434	61/140 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810