Protein Alignment Nsf2 and vcp

DIOPT Version :9

• Sequence 1: NP_001287318.1
• Gene: Nsf2 / 41694
• FlyBaseID: FBgn0266464
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_001005677.1
• Gene: vcp / 448177
• XenbaseID: XB-GENE-969573
• Length: 805
• Species: Xenopus tropicalis
• Alignment Length: 645
• Identity: 183/645 - (28%)
• Similarity: 287/645 - (44%)
• Gaps: 143/645 - (22%)

  Fly   175 RNVRFGRIL----GNTVVQFEKAE-----------NSVLNLQGRSKGKIVRQSIINPDWDFGKMG 224
            |.:|.|.|.    |...|:|:..|           ::|::.:|....:...:..:|   :.|...
 Frog   144 RPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEESLN---EVGYDD 205

  Fly   225 IGGLDKEFNAIFRRAFASRVFPPELVEQLGIKHVKGILLYGPPGTGKTLMARQIGTMLNAREPK- 288
            |||..|:. |..:......:..|.|.:.:|:|..:||||||||||||||:||.:     |.|..
 Frog   206 IGGCRKQL-AQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAV-----ANETGA 264

  Fly   289 ---IVNGPQILDKYVGESEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKARGSVAGNSG 350
               ::|||:|:.|..||||:|:|:.|.|||:....        ||..||:|||...|....|.
 Frog   265 FFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPA--------IIFIDELDAIAPKREKTHGE-- 319

  Fly   351 VHDTVVNQLLAKIDGVEQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIH 415
            |...:|:|||..:||::|..:::|:..|||.:.||.||.|.||.:.:::|.:|:..||::||.||
 Frog   320 VERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDSTGRLEILQIH 384

  Fly   416 TKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMNR---LIKADSKVHVDPEAMEK 477
            ||.|    |::.|||..::|.:|....||:|..|...|...|:.:   ||..:.:. :|.|.|..
 Frog   385 TKNM----KLSDDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDET-IDAEVMNS 444

  Fly   478 LRVTRADFLHALDNDIKPA---------------FGAAQEMLENLLARGIINWGPPV---TELLE 524
            |.||..||..||......|               .|..:::...|  :.::.:  ||   .:.|:
 Frog   445 LAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGGLEDVKREL--QELVQY--PVEHPDKFLK 505

  Fly   525 DGMLSVQQAKATESSGLVSVLIEGAPNSGKSALAANLAQLSDFPFVKVCSPEDM-VGFTESAKCL 588
            .||        |.|.|   ||..|.|..||:.||..:|......|:.:..||.: :.|.||.  .
 Frog   506 FGM--------TPSKG---VLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESE--A 557

  Fly   589 HIRKIFDDAYRSTLSCIV----VDNVER-----LLDYGPIGPRYSNLTLQALLVLLKKQPPKGRK 644
            ::|:|||.| |....|::    :|::.:     :.|.|....|..|..|..:..:..|     :.
 Frog   558 NVREIFDKA-RQAAPCVLFFDELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTK-----KN 616

  Fly   645 LLILCTSSRRDVLEEMEMLSAFTSVLHVSNLSTPENVLAVL----------DDSDL--------- 690
            :.|:..::|.|:::...:.......|....|...::.:|:|          .|.||
 Frog   617 VFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRIAILKANLRKSPVAKDVDLDFLAKMTNG 681

  Fly   691 FSPEELQSIARKMAGKRLCIGIKKLLALIDMI---------RQSEPHQRVIKFLSKMEEE 741
            ||..:|..|.     :|.|     .||:.:.|         ||:.|        |.||.|
 Frog   682 FSGADLTEIC-----QRAC-----KLAIRESIENEIRRERERQTNP--------SAMEVE 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011
		AAA	259..404	CDD:214640	62/148 (42%)
		AAA	261..402	CDD:278434	61/144 (42%)
		AAA	543..674	CDD:214640	33/140 (24%)
		P-loop_NTPase	544..>613	CDD:304359	23/78 (29%)
vcp	NP_001005677.1	CDC48	25..764	CDD:273521	183/645 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	768..805

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910