DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nsf2 and CG16789

DIOPT Version :9

Sequence 1:	NP_001287318.1	Gene:	Nsf2 / 41694	FlyBaseID:	FBgn0266464	Length:	752	Species:	Drosophila melanogaster
Sequence 2:	NP_649910.3	Gene:	CG16789 / 41154	FlyBaseID:	FBgn0037712	Length:	831	Species:	Drosophila melanogaster

Alignment Length:	457	Identity:	89/457 - (19%)
Similarity:	155/457 - (33%)	Gaps:	157/457 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   400 ISLPNEQGRVQILNIHTKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQ---------- 454
            :.||:.:..:.:.| .|.|.:|...:.|.....::....| :...||| ..||..
  Fly   403 VCLPDIRAEIDLFN-DTWRDKDETGVLSQAAYEDMIYSDK-YQEVELE-FRRAVDDVMRQEIELL 464

  Fly   455 STAMNRLIKADSKVHVDPEAMEKLRVTRADFLHALDNDIKPAFGAAQEMLENLLARGIINWGPP- 518
            .||:.:.:|..||         |.|.:........:.|:.|. ...:.:.|.|:..|||...|.
  Fly   465 QTAVGKKVKKSSK---------KTRRSGKKSKKKKEKDLTPD-RTTESLYEELVTNGIIRKYPEL 519

  Fly   519 -VTELLEDGMLSVQQAKATESSG-------------------------LVSVLIEGAPNSGKSAL 557
             :.:.|.|..|:. :.....|.|                         :.|:|:.|...|||.||
  Fly   520 RLKQFLGDKALTA-RIGTNPSPGDIRQILTEYCILPLGSDAIHNCTPLIRSILLAGPKGSGKKAL 583

  Fly   558 AANL-----AQLSDFPFVKVCSPEDMVG--------------FTESAKCLHIRKIF-DDAYRSTL 602
            ...:     |.|.|.      :|.::||              ..:.::.|....|| .||.|..:
  Fly   584 LHAICTEVGAVLFDL------TPANIVGKYPGKSGLIMLIHLVLKVSRLLQPAVIFMGDAERPFM 642

  Fly   603 SCI-----------------VVDNV---ERLLDYGPIGPRYSNLTLQALLVLLKK---------Q 638
            ..|                 ::.|:   :|::..|.     |||..:|...||:.         :
  Fly   643 KKIPKTDRTDPKRLKKDLPKLIKNIAPEDRVVFIGT-----SNLPWEADQKLLQSVYNRFIYIPR 702

  Fly   639 PPKGRKLLILCTSSRRDVLEEMEMLSAFTSVLH-----VSNLSTPENVLAVLDDSDLFSP----- 693
            |..|                  .|..|:.::||     :|||.|  :.:|.:.|......
  Fly   703 PDYG------------------AMSHAWKTLLHDYSGGISNLDT--SAMAKISDGYTIGSIDACL 747

  Fly   694 EELQSIARKMAGKRLCIGIKKLLALI---DMIRQSEPH------------QRVIKFLSKMEEEGG 743
            :|:.:..||:..:...:...:|:.::   |.:.:.|..            :|..:|| ::|||..
  Fly   748 KEVMTCKRKLQLRTQPLTNAELINVLCSRDPVYREEEEAFESWWSKTPLGRRRQRFL-ELEEERL 811

  Fly   744 LE 745
            ||
  Fly   812 LE 813

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011
		AAA	259..404	CDD:214640	1/3 (33%)
		AAA	261..402	CDD:278434	0/1 (0%)
		AAA	543..674	CDD:214640	36/184 (20%)
		P-loop_NTPase	544..>613	CDD:304359	21/108 (19%)
CG16789	NP_649910.3	AAA	568..704	CDD:214640	30/146 (21%)
CG16789	NP_649910.3	AAA	570..702	CDD:278434	29/142 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900