Protein Alignment Nsf2 and nvl

DIOPT Version :9

• Sequence 1: NP_001287318.1
• Gene: Nsf2 / 41694
• FlyBaseID: FBgn0266464
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_998649.1
• Gene: nvl / 406805
• ZFINID: ZDB-GENE-040426-2871
• Length: 796
• Species: Danio rerio
• Alignment Length: 534
• Identity: 158/534 - (29%)
• Similarity: 236/534 - (44%)
• Gaps: 117/534 - (21%)

  Fly    53 LEKISGPELPLGHVGFSLVQRKWATL---SIN--------QEID-VRPYRFDASAD--------I 97
            |.|||.|||..|..|.|  ::|...|   :|:        .||| :.|.|..||.|        :
Zfish   288 LLKISAPELVSGVSGES--EQKLRELFEQAISSAPCILFIDEIDAITPKRETASKDMERRIVAQL 350

  Fly    98 ITLVSFETDFLQKKT-----TTQEPYDSDEMAKEFLMQF-----AGMP-----LTVGQTLVFQFK 147
            :|.:......|:...     .|..| ||.:.|.....:|     .|:|     :.:.:||..:.:
Zfish   351 LTCMDDLNSMLEPAQVLVIGATNRP-DSLDPALRRAGRFDREICLGIPDEGARMKILKTLCRKIR 414

  Fly   148 ---DKKFLGLAVKT----------------LEAV-----DPRTVGDSLPKTRNVRFGRILGNTV- 187
               |..|..||..|                :.||     :|.|.....|.....|...:|.::|
Zfish   415 LPDDFDFRHLARLTPGYVGADLMALCREAAMNAVNRILLEPTTEDQITPTLALARLLDLLKSSVS 479

  Fly   188 ----------VQFEKAENSVLNLQGRSKGKIVRQSIIN-PD--WDFGKMGIGGLDKEFNAIFRRA 239
                      |......:|::.:|..:|    |:.... ||  |    ..:|.| ::.......|
Zfish   480 LSEDQLAALCVLMSDFSSSLVRVQPSAK----REGFATVPDVTW----ADVGAL-QDVREELHMA 535

  Fly   240 FASRVFPPELVEQLGIKHVKGILLYGPPGTGKTLMARQIGTM--LNAREPKIVNGPQILDKYVGE 302
            ..:.:..||..:.||:....|:||.||||.||||:|:.:...  ||...   |.||::|:.||||
Zfish   536 IMAPIQNPEQFKALGLSAPAGLLLAGPPGCGKTLLAKAVANASGLNFIS---VKGPELLNMYVGE 597

  Fly   303 SEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKARGSVAGNSGVHDTVVNQLLAKIDGVE 367
            ||..:|::|        :.|.||...:|.||||||:|..|..  ..||....||||||.::||:|
Zfish   598 SERAVRQVF--------QRGRNSAPCVIFFDEIDALCPRRSE--HESGASVRVVNQLLTEMDGME 652

  Fly   368 QLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHTKRMRDFNKIASDVDNN 432
            ....:.::..|||.|:||.|:||||||:..:.:.||....|..|||..||.... .::.|||...
Zfish   653 NRRQVFIMAATNRPDIIDPAVLRPGRLDKTLYVGLPPAADRHAILNTITKGGTK-PQLDSDVSLE 716

  Fly   433 EIA--AKTKNFSGAELEGLVRAAQSTAMNRLIKADSKVHVDP-----EAMEKLRVTRADFLHALD 490
            |||  |:.:.|:||:|..|||.|...|:        :||:||     |:.:.:||:|..|..|.
Zfish   717 EIAHDARCETFTGADLSALVREACVNAL--------RVHLDPAQTHTESAKDIRVSRVHFEDAF- 772

  Fly   491 NDIKPAFGAAQEML 504
            ..::|:.....:::
Zfish   773 KKVRPSVSKKDQLM 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012	16/47 (34%)
		CDC48_2	117..>170	CDD:215011	18/86 (21%)
		AAA	259..404	CDD:214640	63/146 (43%)
		AAA	261..402	CDD:278434	61/142 (43%)
		AAA	543..674	CDD:214640
		P-loop_NTPase	544..>613	CDD:304359
nvl	NP_998649.1	Nucleolin_bd	2..71	CDD:293330
		RNA_polI_A34	<165..215	CDD:285426
		SpoVK	246..792	CDD:223540	158/534 (30%)
		AAA	264..395	CDD:278434	29/109 (27%)
		P-loop_NTPase	537..>573	CDD:304359	16/35 (46%)
		AAA	557..687	CDD:278434	61/142 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900