DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsf2 and atad1a

DIOPT Version :9

Sequence 1:	NP_001287318.1	Gene:	Nsf2 / 41694	FlyBaseID:	FBgn0266464	Length:	752	Species:	Drosophila melanogaster
Sequence 2:	NP_001004640.1	Gene:	atad1a / 368672	ZFINID:	ZDB-GENE-030616-593	Length:	380	Species:	Danio rerio

Alignment Length:	362	Identity:	91/362 - (25%)
Similarity:	157/362 - (43%)	Gaps:	75/362 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 LEAVDPRTVGDSLPKTRNVRFGRILGNTVVQFEKAENSVLNLQGRSKGKIVRQSIINPDWDFGKM 223
            ::|:||.....|..|.|..:..:.:|...|...:.|.::..|       :|....|...|    .
Zfish    41 VDALDPTQKQKSQAKKRAEQLMKQIGVEGVSLTEYEMNIATL-------LVDPRSIKVTW----R 94

  Fly   224 GIGGLDKEFNAI---------FRRAFA-SRVFPPELVEQLGIKHVKGILLYGPPGTGKTLMARQI 278
            .:.|||:..:.:         .|..|: |::..|.          ||:|||||||.||||:|:..
Zfish    95 DVAGLDEIISEMQDTVILPFQKRHLFSGSKLLQPP----------KGVLLYGPPGCGKTLIAKAT 149

  Fly   279 GTMLNAREPKIVN--GPQILDKYVGESEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKA 341
            ......|   .:|  ...:.||:.|||:.....:|:.|    .::.|    .||..||||:..:.
Zfish   150 AKASGCR---FINLQASTLTDKWYGESQKLTAAVFSLA----VKIQP----CIIFLDEIDSFLRN 203

  Fly   342 RGSVAGNSGVHDTVV---NQLLAKIDGVEQLNN--ILVIGMTNRRDMIDEALLRPGRLEVQMEIS 401
            |.|:.     |:...   .|.::..||::...|  ::|:|.|||...:|.|:||  |:.....:.
Zfish   204 RSSMD-----HEATAMMKAQFMSLWDGLDTGENSQVMVMGATNRPQDVDAAILR--RMPTAFHVG 261

  Fly   402 LPNEQGRVQILNIHTKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMNRLIKA-- 464
            |||...|.:||.:    :.....:::.::..|||::::.:||::|:.|.|.|....:...::.
Zfish   262 LPNAAQREEILRL----ILSGENLSNAINLKEIASQSEGYSGSDLKELCRDAAMYRVRDYVRKQQ 322

  Fly   465 -----------DSKVHVDPEAMEKLRVTRADFLHALD 490
                       :.:.|||...:..  ||:.|.|..||
Zfish   323 MKQIAQQFQLDEEEEHVDSRQLRP--VTQLDLLFGLD 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011	3/10 (30%)
		AAA	259..404	CDD:214640	48/151 (32%)
		AAA	261..402	CDD:278434	45/147 (31%)
		AAA	543..674	CDD:214640
		P-loop_NTPase	544..>613	CDD:304359
atad1a	NP_001004640.1	AAA	128..254	CDD:214640	47/153 (31%)
atad1a	NP_001004640.1	AAA	132..262	CDD:278434	45/147 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900