DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsf2 and atad1b

DIOPT Version :9

Sequence 1:	NP_001287318.1	Gene:	Nsf2 / 41694	FlyBaseID:	FBgn0266464	Length:	752	Species:	Drosophila melanogaster
Sequence 2:	NP_001019592.1	Gene:	atad1b / 368412	ZFINID:	ZDB-GENE-030616-44	Length:	362	Species:	Danio rerio

Alignment Length:	373	Identity:	96/373 - (25%)
Similarity:	161/373 - (43%)	Gaps:	105/373 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 LEAVDPRTVGDSLPKTRNVRFGRILGNTVVQFEKAENSVLNLQGRSKGKI------VRQSIINP- 216
            ::|:||         ||..:         |:.:|....::...|....|:      :...:::|
Zfish    42 VDAIDP---------TRKQK---------VEAQKQAEKLMRQIGVQNVKLSEYEMSIAAHLVDPL 88

  Fly   217 ----DWDFGKMGIGGLDKEFNAI---------FRRAF-ASRVFPPELVEQLGIKHVKGILLYGPP 267
                .|    ..|.|||:....:         .|..| .||:..|.          ||:||||||
Zfish    89 TMQITW----YDIAGLDEVITELKDTVILPIQKRHLFEGSRLLQPP----------KGVLLYGPP 139

  Fly   268 GTGKTLMARQIGTMLNAREP--KIVN-GPQIL-DKYVGESEANIRRLFAEAEEEEKRLGPNSGLH 328
            |.||||:|:     ..|:|.  :.:| .|..| ||:.|||:.....:|:.|    .:|.|:
Zfish   140 GCGKTLIAK-----ATAKEAGFRFINLQPSTLTDKWYGESQKLAAAVFSLA----IKLQPS---- 191

  Fly   329 IIIFDEIDAICKARGSVAGNSGVHDTVV---NQLLAKIDGVEQLNN--ILVIGMTNRRDMIDEAL 388
            ||..||||:..:.|     :|..|:...   .|.::..||::...|  ::::|.|||...:|.|:
Zfish   192 IIFIDEIDSFLRNR-----SSSDHEATAMMKAQFMSLWDGLDTDYNCQVIIMGATNRPQDLDSAI 251

  Fly   389 LRPGRLEVQMEISLPNEQGRVQILNIHTKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAA 453
            ||  |:..:..|:.||.:.|..||    |.:.:...:.|.|:.:|||.:|..|||::|..:.|.|
Zfish   252 LR--RMPTRFHINQPNARQRKDIL----KLILENENVESAVELSEIAKQTDGFSGSDLREMCRDA 310

  Fly   454 QSTAMNRLIKADSKVHVDPE--------------AMEKLRVTRADFLH 487
            ....:...:..:|     ||              |:||::.:::..:|
Zfish   311 ALLCVRDFVHQES-----PEEDFIRPIRQEDLQRAIEKMKKSKSAGVH 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011	3/10 (30%)
		AAA	259..404	CDD:214640	51/153 (33%)
		AAA	261..402	CDD:278434	49/149 (33%)
		AAA	543..674	CDD:214640
		P-loop_NTPase	544..>613	CDD:304359
atad1b	NP_001019592.1	AAA	129..258	CDD:214640	51/158 (32%)
atad1b	NP_001019592.1	AAA	133..261	CDD:278434	48/147 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900