DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsf2 and Fign

DIOPT Version :9

Sequence 1:	NP_001287318.1	Gene:	Nsf2 / 41694	FlyBaseID:	FBgn0266464	Length:	752	Species:	Drosophila melanogaster
Sequence 2:	NP_001099954.1	Gene:	Fign / 295649	RGDID:	1308174	Length:	759	Species:	Rattus norvegicus

Alignment Length:	338	Identity:	87/338 - (25%)
Similarity:	144/338 - (42%)	Gaps:	64/338 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 EKAENSVLNLQGRSKGKIVRQSIINP--DWDFGKMGIGGLDKEFNAIFRRAFASRVFPPELVEQL 253
            |:.:|:..:|......:|:.|   .|  ||.    .|.|||     :.:......|..|.|....
  Rat   459 EQLKNTDTHLIDLVTNEIITQ---GPPVDWS----DIAGLD-----LVKAVIKEEVLWPVLRSDA 511

  Fly   254 --GIKHV-KGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVGESEANIRRLFAEAE 315
              |:..: :.|||:||.||||||:.|.|.:.|.|...||. |..::.|::||:|..|...|..|.
  Rat   512 FSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIA-GSGLVAKWLGEAEKIIHASFLVAR 575

  Fly   316 EEEKRLGPNSGLHIIIFDEIDAICKARGSVAGNSGVHDTVV---NQLLAKIDGV--EQLNNILVI 375
            ..:    |:    :|...:||.:..::.|..     |..|.   .:.|.::|.|  ...:.|:||
  Rat   576 CRQ----PS----VIFVSDIDMLLSSQVSEE-----HSPVSRMRTEFLMQLDTVLTSAEDQIVVI 627

  Fly   376 GMTNRRDMIDEALLR--PGRLEVQMEISLPNEQGRVQILNIHTKRMRDFNKIASDVDNNEIAAKT 438
            ..|::.:.|||:|.|  ..||.:.:..|....|..||:|:.|       |...:|.:...:..:|
  Rat   628 CATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQH-------NYCLNDKEFALLVQRT 685

  Fly   439 KNFSGAELEGLVRAAQSTAMNRLIKADSKVHVDPEAMEKLRVTRADFLHALDNDIKPA------- 496
            :.|||.::..|.:.|....::.:...|... :.|..:..  :|..||.:|... |:|:
  Rat   686 EGFSGLDVAHLCQEAAVGPLHAMPATDLSA-IMPSQLRP--ITYQDFENAFCK-IQPSISQKELD 746

  Fly   497 --------FGAAQ 501
                    ||.:|
  Rat   747 MYVEWNKMFGCSQ 759

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011
		AAA	259..404	CDD:214640	47/151 (31%)
		AAA	261..402	CDD:278434	46/147 (31%)
		AAA	543..674	CDD:214640
		P-loop_NTPase	544..>613	CDD:304359
Fign	NP_001099954.1	AAA	519..654	CDD:214640	46/148 (31%)
		AAA	522..652	CDD:278434	46/143 (32%)
		Vps4_C	<723..756	CDD:286426	6/35 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900