DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nsf2 and CG31495

DIOPT Version :9

Sequence 1:	NP_001287318.1	Gene:	Nsf2 / 41694	FlyBaseID:	FBgn0266464	Length:	752	Species:	Drosophila melanogaster
Sequence 2:	NP_001287320.1	Gene:	CG31495 / 261626	FlyBaseID:	FBgn0051495	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	354	Identity:	140/354 - (39%)
Similarity:	202/354 - (57%)	Gaps:	36/354 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   398 MEISLPNEQGRVQILNIHTKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMNRLI 462
            :.|:|||.:.||.:|.....|:.|.. :|.||...|||.|||||:..||..|||.|       |.
  Fly     2 VNITLPNTEERVNLLKSRINRLGDIT-VAGDVCAREIAMKTKNFTEDELCQLVREA-------LH 58

  Fly   463 KADSKVHVDPEAMEKLRVTRADFLHALDNDIKPAFGAAQEMLENLLARGIINWGPPVTELLEDGM 527
            :|..:.|| ....:.|:||:.|.|.|: ..|:|.||..:|.|:.|:         |...|
  Fly    59 EAIVRTHV-TRCPKGLQVTQVDLLAAV-KIIQPRFGRQEETLQLLM---------PYEYL----- 107

  Fly   528 LSVQQAKATESSGLVSV--------LIEGAPNSGKSALAANLAQLSDFPFVKVCSPEDMVGFTES 584
                ...|.:.:.|:|.        |:||.|.||.:.:||.:|..:|.||:|..|..:::|.::|
  Fly   108 ----DRTAFDPNDLLSTGRPRWSCHLVEGKPKSGLTTVAAQMALKTDCPFIKYISSAELLGLSDS 168

  Fly   585 AKCLHIRKIFDDAYRSTLSCIVVDNVERLLDYGPIGPRYSNLTLQALLVLLKKQPPKGRKLLILC 649
            .||..||::.:|||.|..||:::|:.||::.||.:|.|||...||.|.||||||||...:|:|:|
  Fly   169 EKCQRIREVLEDAYVSRRSCVIIDDFERVIGYGALGKRYSKEFLQKLTVLLKKQPPNSHELIIIC 233

  Fly   650 TSSRRDVLEEMEMLSAFTSVLHVSNLSTPENVLAVLDDSDLFSPEELQSIARKMAGKRLCIGIKK 714
            ||:|.|||||:.:||.||||.:|.|:|||:.::.:::.|..|.||||:.|...|.|:.:.||||:
  Fly   234 TSNRLDVLEELGLLSVFTSVHNVPNVSTPKELMVIVEASKRFEPEELRQIEIAMDGRNVSIGIKR 298

  Fly   715 LLALIDMIRQSEPHQRVIKFLSKMEEEGG 743
            ||.||..:....|.:|..|.|.|:.|..|
  Fly   299 LLDLIAWVNSLNPDRRAAKLLKKLGEAMG 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011
		AAA	259..404	CDD:214640	2/5 (40%)
		AAA	261..402	CDD:278434	1/3 (33%)
		AAA	543..674	CDD:214640	65/138 (47%)
		P-loop_NTPase	544..>613	CDD:304359	28/76 (37%)
CG31495	NP_001287320.1	AAA	129..259	CDD:214640	64/129 (50%)
CG31495	NP_001287320.1	P-loop_NTPase	129..257	CDD:304359	63/127 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449918
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S525
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D197562at2759
OrthoFinder	1	1.000	-	-		FOG0003053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23078
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.800