DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsf2 and Pex6

DIOPT Version :9

Sequence 1:	NP_001287318.1	Gene:	Nsf2 / 41694	FlyBaseID:	FBgn0266464	Length:	752	Species:	Drosophila melanogaster
Sequence 2:	NP_663463.1	Gene:	Pex6 / 224824	MGIID:	2385054	Length:	981	Species:	Mus musculus

Alignment Length:	270	Identity:	93/270 - (34%)
Similarity:	150/270 - (55%)	Gaps:	41/270 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 PELVEQLGIKHVKGILLYGPPGTGKTLMARQIG-----TMLNAREPKIVNGPQILDKYVGESEAN 306
            |||: .||::. .|:||:|||||||||:|:.:.     |.|:      |.||::::.|||:||.|
Mouse   729 PELL-SLGLRR-SGLLLHGPPGTGKTLLAKAVATECSLTFLS------VKGPELINMYVGQSEEN 785

  Fly   307 IRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKARGSVAGNSGVHDTVVNQLLAKIDGVEQLNN 371
            :|.:||.|    :...|    .||.|||:|::..:||....:.||.|.||:||||::||:....:
Mouse   786 VREVFARA----RAAAP----CIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHSTQD 842

  Fly   372 ILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQ-GRVQILNIHTKRMRDFNKIASDVD-NNEI 434
            :.|||.|||.|::|.|||||||.:..:.:....:: .::::|:..|::.    |:.:.|. .|.:
Mouse   843 VFVIGATNRPDLLDPALLRPGRFDKLVFVGASEDRASQLRVLSAITRKF----KLEASVSLANVL 903

  Fly   435 AAKTKNFSGAELEGLVRAAQSTAMNRLIKADSKVHVDPEAMEKLR-----VTRADFLHALDNDIK 494
            .......:||:|..|...|..||:.|.::       |.|...:||     :|..|.|.|... ::
Mouse   904 DCCPPQLTGADLYSLCSDAMMTALKRRVR-------DLEEGLELRSSALLLTMEDLLQAAAR-LQ 960

  Fly   495 PAFGAAQEML 504
            |:. :.||:|
Mouse   961 PSV-SEQELL 969

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011
		AAA	259..404	CDD:214640	63/149 (42%)
		AAA	261..402	CDD:278434	62/145 (43%)
		AAA	543..674	CDD:214640
		P-loop_NTPase	544..>613	CDD:304359
Pex6	NP_663463.1	SpoVK	464..968	CDD:223540	91/267 (34%)
		AAA	467..596	CDD:278434
		AAA	744..872	CDD:278434	60/141 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900