DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsf2 and pch-2

DIOPT Version :9

Sequence 1:	NP_001287318.1	Gene:	Nsf2 / 41694	FlyBaseID:	FBgn0266464	Length:	752	Species:	Drosophila melanogaster
Sequence 2:	NP_495711.1	Gene:	pch-2 / 174313	WormBaseID:	WBGene00008641	Length:	424	Species:	Caenorhabditis elegans

Alignment Length:	303	Identity:	69/303 - (22%)
Similarity:	133/303 - (43%)	Gaps:	62/303 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 EFNAIFRRAFASRVFPPELVE------QLGIKHV--------KGILLYGPPGTGKTL----MARQ 277
            ||::|:...........|::.      :|..|||        :.|||.||||||||.    :|:.
Worm   131 EFDSIWENLIYDSNLKNEVMSYVAALARLSEKHVNTKIINVNRLILLTGPPGTGKTSLCKGLAQH 195

  Fly   278 IGTMLNAREPKIV----NGPQILDKYVGESEANIRRLFAEAEE--EEKRLGPNSGLHIIIFDEID 336
            :...:|.:..|.|    |...:..|:..||...::::|.:.:|  |:::.     :..::.||::
Worm   196 LSIRMNDKYSKSVMLEINSHSLFSKWFSESGKLVQKMFDQIDELAEDEKC-----MVFVLIDEVE 255

  Fly   337 AICKARGSVAGNSGVHDTV--VNQLLAKIDGVEQLNNILVIGMTNRRDMIDEALLRPGRLEVQME 399
            ::...|.|.:..|...|.:  ||.||.:||.:.:.:|:|::..:|....:|:||:  .|.::...
Worm   256 SLGMCRESSSSRSEPSDAIRAVNALLTQIDRIRRRDNVLILCTSNLESTLDKALV--DRADIVKN 318

  Fly   400 ISLPNEQGRVQILNIHTKRMRDFNKIASDVDN------------------NE-------IAAKTK 439
            :..|::..|..:|.   ..:.:..:|...:||                  ||       ||.:.:
Worm   319 VGQPSDFARYSMLK---SSIMELARIGVVIDNEVHTDYWPQDICDTKAPRNEFTEILFKIAQEAR 380

  Fly   440 NFSGAELEGLVRAAQSTAMNRLIKADSKVHVDPEAMEKLRVTR 482
            ..||..:..|.....|.:....|...:.:::..||: |.|::|
Worm   381 GLSGRAISMLPTLVYSKSPEETITLPNCMNLFLEAV-KERLSR 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_001287318.1	CDC48_N	9..89	CDD:215012
		CDC48_2	117..>170	CDD:215011
		AAA	259..404	CDD:214640	41/156 (26%)
		AAA	261..402	CDD:278434	41/152 (27%)
		AAA	543..674	CDD:214640
		P-loop_NTPase	544..>613	CDD:304359
pch-2	NP_495711.1	AAA	172..322	CDD:214640	41/156 (26%)
pch-2	NP_495711.1	AAA	175..320	CDD:278434	41/151 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810