Protein Alignment Nsf2 and LOC1280704

DIOPT Version :10

• Sequence 1: NP_788676.1
• Gene: Nsf2 / 41694
• FlyBaseID: FBgn0266464
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: XP_320566.4
• Gene: LOC1280704 / 1280704
• VectorBaseID: AGAMI1_011266
• Length: 860
• Species: Anopheles gambiae
• Alignment Length: 751
• Identity: 147/751 - (19%)
• Similarity: 258/751 - (34%)
• Gaps: 207/751 - (27%)

  Fly     2 SIEKAHRMRAIKCPTDELSLTNKAIVNVSDFTEEVKYVDISPGPGLHYIFALEKISGPELPLGH- 65
            :||..|....|:....||.|  :.:| :|:..||:....:.|...:.....|:...|..|.|.|
Mosquito    84 AIEAQHDRTEIQGQVFELYL--RYLV-ISNRLEEIYDQIVQPQKRILIRKLLDNCLGRMLELKHD 145

  Fly    66 ------VGFS---LVQRKWATLSINQEIDV-RPYRFDASADIITLVSFETDFLQKKTTTQEPYDS 120
                  ..||   .:..|.....::.|:.| |.:|.:....:.....|..|.|:|.....|
Mosquito   146 LVIIDMTEFSYNDAIVEKLGLTPLSMEVAVPRYFRREREEQLNERKKFMDDILKKIGALDE---- 206

  Fly   121 DEMAKEFLMQFAGMPLTVGQT--------LVFQF-KDKKFLGLAVKTLEAVDPRTVG----DSLP 172
             |:.:|.|.:...  :.:.||        |..|| |:.|.|....|...:.|..|.|    ..:.
Mosquito   207 -EVVEEELSELEA--IRIIQTHERARQGRLRAQFMKELKLLKEKGKPDSSRDKSTTGLNAAMKIQ 268

  Fly   173 KT-------RNVRFGR-----ILGNTVVQFEKAENSVLNLQGRSKGKIVRQSIINPDWDFG---- 221
            ||       |..|..:     ::|........|..::..|:...:.:..:|.....|::..
Mosquito   269 KTWRGYATRRQTRRKKMEEMILIGMVPAPVTSARTALDELEDLKQFRYKQQKTFQDDYERSLVRV 333

  Fly   222 ------KMGIG---GLDKEFNAIFRRAFASRV-----FPPELVEQLGIKHVKGILLYGPPGTGKT 272
                  |.|..   .:..|....|:. :..|.     ||.|  |..|.:|     |....|| ::
Mosquito   334 KEEISVKQGAAMTEDIADEIRTWFKE-YQKRTGRLPDFPSE--EAGGSRH-----LLSRQGT-ES 389

  Fly   273 LMARQIGTMLNAREPKIVNG--PQILDKYVGE--SEANIRRLFAEAEE----EEKRLGPNSGLHI 329
            .|:|  .::|::||.|:...  .::..|..||  .|..:.:.|...:.    |.|     ||:
Mosquito   390 EMSR--SSVLSSRESKLKGSGKEKLAQKKPGELSLEEGLDKAFKPMQSSFLPEIK-----SGI-- 445

  Fly   330 IIFDEIDAICKARGSVAGNSGVHDTVVNQLL--AKIDGVEQLNNILVIGMTNRRDMIDEALLRPG 392
               :|...:.|.:..   :..:..|..:.::  .|...||          ...|.::||.:
Mosquito   446 ---EEYTEVWKGKDE---SQNLRQTYYDDMIYEEKYADVE----------AELRRIVDEIM---- 490

  Fly   393 RLEVQ-MEISLPNEQGRVQILNIHTKRMRDFNKIASDVDNNEIAAKTKNFSGAEL--EGLVRAAQ 454
            |.|:: ::|:|..::|..::.....|..|...|.....|.:....:|......||  .|:::...
Mosquito   491 RQELELLQIALERDRGGKKLKKSSKKARRSGKKGKKKKDKDLTPDRTTESLFEELVTNGIIKKYP 555

  Fly   455 STAMNRLIKADSKVHVDPEAMEKLRVTRADFLHALDNDIKPAFGAAQEMLEN--LLARG---IIN 514
            .|.:...:                    .|..:|..:.:.|:.|..:::::.  :|..|   |.|
Mosquito   556 ETPIKSYV--------------------GDLSYAARSALNPSPGDVRQLIKQYCILPLGSETIRN 600

  Fly   515 WGPPVTELL-----EDGMLSVQQAKATESSGLVSVLIEGAPNS------GKSAL---------AA 559
            :||.:..||     ..|..|:..|..||:.   |||.:.:|.:      |||.|         .:
Mosquito   601 FGPCIKSLLIAGPKGSGKTSLVHAICTETG---SVLFDISPPNIVGKYPGKSGLIMLMHLISKVS 662

  Fly   560 NLAQLS----------------------------DFP-FVKVCSPEDMVGFTESAKCLHIRKIFD 595
            .|.|.|                            |.| .||...|||.:....::.|
Mosquito   663 RLLQPSVIYFGDAEKPFMKKIPKTDRTDPKRLKKDLPKLVKNIQPEDRIMLIGTSDC-------- 719

  Fly   596 DAYRSTLSCIVVDNVERLL-----DYGPIGPRYSNL 626
             .:...:. ::|...:|.:     |||.:...:..|
Mosquito   720 -PWEGDMK-LMVQTYQRFIYIPRPDYGALSFAWKEL 753

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nsf2	NP_788676.1	CDC48_N	9..89	CDD:215012	20/90 (22%)
		CDC48_2	117..>170	CDD:215011	15/65 (23%)
		RecA-like_NSF-SEC18_r1-like	224..400	CDD:410912	39/194 (20%)
		CDC48	<225..>611	CDD:273521	87/460 (19%)
LOC1280704	XP_320566.4	None