DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9288 and ABITRAM

DIOPT Version :9

Sequence 1:	NP_650316.1	Gene:	CG9288 / 41689	FlyBaseID:	FBgn0260464	Length:	214	Species:	Drosophila melanogaster
Sequence 2:	NP_060302.1	Gene:	ABITRAM / 54942	HGNCID:	1364	Length:	181	Species:	Homo sapiens

Alignment Length:	158	Identity:	71/158 - (44%)
Similarity:	97/158 - (61%)	Gaps:	11/158 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 PSVVDRFFTRYYYFKGDV------PYQVLYHSNRICLICLAPEHPALAQG--ISSVNFDIG-NVD 93
            ||:|||:|||:|  |.||      .:.:|.||||||:|.||..||.|..|  |.|:::.|. |..
Human    13 PSLVDRYFTRWY--KPDVKGKFCEDHCILQHSNRICVITLAESHPVLQSGKTIKSISYQISTNCS 75

  Fly    94 RSQNVVKGKGKKGGMILQAESTLALLTTANGGTYKVPSCIRGKLVEVNTAIVEEPKLLEQLPEGA 158
            |.||.|.||.|:|...|...:.|..:..::|..|.|.||:||:|:|||..|:.:|.:|::.|...
Human    76 RLQNKVSGKFKRGAQFLTELAPLCKIYCSDGEEYTVSSCVRGRLMEVNENILHKPSILQEKPSTE 140

  Fly   159 GYFAILLPKIENCDAIKASLLTQEQYEE 186
            ||.|::|||.|...:|...||||:||||
Human   141 GYIAVVLPKFEESKSITEGLLTQKQYEE 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9288	NP_650316.1	Biotinyl_lipoyl_domains	<129..189	CDD:299706	29/58 (50%)
ABITRAM	NP_060302.1	Biotinyl_lipoyl_domains	<115..171	CDD:325020	26/54 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155486
Domainoid	1	1.000	66	1.000	Domainoid score	I10009
eggNOG	1	0.900	-	-		E1_KOG3266
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56788
Inparanoid	1	1.050	127	1.000	Inparanoid score	I4698
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53738
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006221
OrthoInspector	1	1.000	-	-		oto90946
orthoMCL	1	0.900	-	-		OOG6_104035
Panther	1	1.100	-	-	LDO	PTHR13651
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2921
SonicParanoid	1	1.000	-	-		X5162
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.790