Protein Alignment CG9297 and SLA1

DIOPT Version :10

• Sequence 1: NP_788674.1
• Gene: CG9297 / 41688
• FlyBaseID: FBgn0038181
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_009546.1
• Gene: SLA1 / 852276
• SGDID: S000000103
• Length: 1244
• Species: Saccharomyces cerevisiae
• Alignment Length: 719
• Identity: 145/719 - (20%)
• Similarity: 222/719 - (30%)
• Gaps: 260/719 - (36%)

  Fly   328 ENADDDDD------DDDEDDKEAVKKR---SKRE----------VDAAPVL-------DIEAPPS 366
            |.|..:||      ..|.||...||||   |..|          ::.||||       |.|...:
Yeast    21 ELAIQEDDLLYLLQKSDIDDWWTVKKRVIGSDSEEPVGLVPSTYIEEAPVLKKVRAIYDYEQVQN 85

  Fly   367 PAEEFPVEEEIVKEASAEEEAEVEAVKEE-------------EPE------QE----AVQEPEPE 408
            ..||....|..|.:...:::|:...||..             |||      ||    |.:.|...
Yeast    86 ADEELTFHENDVFDVFDDKDADWLLVKSTVSNEFGFIPGNYVEPENGSTSKQEQAPAAAEAPAAT 150

  Fly   409 PVVEP-EAEVQPE---PVQQEEEKAESAEAKEEEKPAPVEEAEAEEESVQPEAAPKEPEAVQEEA 469
            |...| .|.|.|.   |..|..::|...::||::.|       .|:|...|.|.|..|.|..|
Yeast   151 PAAAPASAAVLPTNFLPPPQHNDRARMMQSKEDQAP-------DEDEEGPPPAMPARPTATTE-- 206

  Fly   470 QEDEPQTDGAQDAA--------DDDDDTKPEDELLWEGHIPENRRSRQHITELLQLDEEFNAREK 526
                 .||....|.        .|:|:...||:..:..:   :.....|         |:|. |.
Yeast   207 -----TTDATAAAVRSRTRLSYSDNDNDDEEDDYYYNSN---SNNVGNH---------EYNT-EY 253

  Fly   527 ATDNVAEIILRDIKR----IYENAVK-----------PLETLYKYRDLSNRH----FSDPEIFSK 572
            .:.||.||..|..|:    |..|.:.           .::.|..| |...:|    |.||
Yeast   254 HSWNVTEIEGRKKKKAKLSIGNNKINFIPQKGTPHEWSIDKLVSY-DNEKKHMFLEFVDP----- 312

  Fly   573 PLILFMGPWSGGKSSILNYLTDNEYTPNSLRTGAEPSPAYFNILMWGNETEVLDGTQLAADYTFA 637
                                    |....|.|              ||.|...:...:..:|.
Yeast   313 ------------------------YRSLELHT--------------GNTTTCEEIMNIIGEYK-- 337

  Fly   638 GLQKFGQGLEERLRGLKMKSKILEKVNIVEIPGILEVRKQVSRVFPFNDACQWFIDRADIIFLVY 702
                 |...:..||.::|.|| .:|..||:...:.|.:.:::            |...|.::
Yeast   338 -----GASRDPGLREVEMASK-SKKRGIVQYDFMAESQDELT------------IKSGDKVY--- 381

  Fly   703 DPAKLDVGPETEAILDQLKGREYQTRIILNKADTVKPEELLRVQGALIWNISPLMSSAQPPLMYT 767
                         |||..|.::                          |.:..|:.|.:..|:
Yeast   382 -------------ILDDKKSKD--------------------------WWMCQLVDSGKSGLV-- 405

  Fly   768 TSLWTHPYQDGAPARLLLAQERAFLRDLRTAIDKRIEHKIA-SARRFAVRVRN----HAKMVDCY 827
                  |.|...|.|     ::.......:.|.|.|:.... |..|...|.|:    :|...|..
Yeast   406 ------PAQFIEPVR-----DKKHTESTASGIIKSIKKNFTKSPSRSRSRSRSKSNANASWKDDE 459

  Fly   828 LNTFNNHKTLFGNKKRIADDIIDHPQNYHIYEGLSTLTNISRYDLPDPEVYRDFFRLNPLYEFKK 892
            |.  |:.......|:.....:..|.:|       |:.|.    |.|:|:..|.:...:..::..
Yeast   460 LQ--NDVVGSAAGKRSRKSSLSSHKKN-------SSATK----DFPNPKKSRLWVDRSGTFKVD- 510

  Fly   893 LRDTCTYFRGCPITKLDLAIAYELPELAGKYKKMSEAALAAIEA---------QQQDGTIGQAEP 948
                 ..|.||...|:.|..|..: ::|....|:|...||.:|.         :..||:..:...
Yeast   511 -----AEFIGCAKGKIHLHKANGV-KIAVAADKLSNEDLAYVEKITGFSLEKFKANDGSSSRGTD 569

  Fly   949 KRTS 952
            .|.|
Yeast   570 SRDS 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9297	NP_788674.1	MSCRAMM_ClfA	<93..367	CDD:468110	19/64 (30%)
		TSP3 repeat_long	167..205	CDD:275366
		EHD_N	539..570	CDD:465295	10/49 (20%)
		EHD	574..813	CDD:206740	35/239 (15%)
SLA1	NP_009546.1	SH3_Sla1p_1	7..64	CDD:212707	13/42 (31%)
		SH3	73..127	CDD:473055	9/53 (17%)
		SH3_Sla1p_3	356..412	CDD:212709	16/117 (14%)
		SHD1	489..554	CDD:427630	16/75 (21%)
		SAM_SLA1_fungal	655..716	CDD:188931
		DUF5585	<723..1040	CDD:465521
		Med15	967..>1230	CDD:312941