DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9297 and EHD1

DIOPT Version :9

Sequence 1:	NP_001262553.1	Gene:	CG9297 / 41688	FlyBaseID:	FBgn0038181	Length:	952	Species:	Drosophila melanogaster
Sequence 2:	NP_001030731.1	Gene:	EHD1 / 821573	AraportID:	AT3G20290	Length:	545	Species:	Arabidopsis thaliana

Alignment Length:	424	Identity:	112/424 - (26%)
Similarity:	214/424 - (50%)	Gaps:	46/424 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   521 FNAREKATDNVAEI--ILRDIKRIYENAVKPLETLYKYRDLSNRHFSDPEIFSKPLILFMGPWSG 583
            |:::.....:::.:  |:..:||:|...:||||..|::.|..:...::.:..:||:::.:|.:|.
plant   144 FSSKSSKKISLSSVTSIVDGLKRLYIQKLKPLEVAYRFNDFVSPLLTNSDFDAKPMVMLLGQYST 208

  Fly   584 GKSSILNYLTDNEYTPNSLRTGAEPSPAYFNILMWGNETEVLDGTQLA--ADYTFAGLQKFGQGL 646
            ||::.:.:|..:.| |.: ..|.||:...|.::|.|.:...:.|..:|  ||..|:||..||...
plant   209 GKTTFIKHLLKSTY-PGA-HIGPEPTTDRFVVVMSGPDERSIPGNTVAVQADMPFSGLTTFGTAF 271

  Fly   647 EERLRGLKMKSKILEKVNIVEIPGILEVRKQ-VSRVFPFNDACQWFIDRADIIFLVYDPAKLDVG 710
            ..:....:|...:||.|..|:.||:|...|| ..|.:.|.....||..:.|:|.|::||.||||.
plant   272 LSKFECSQMPHPLLEHVTFVDTPGVLSGEKQRTQRAYDFTGVTSWFASKCDLILLLFDPHKLDVS 336

  Fly   711 PETEAILDQLKGREYQTRIILNKADTVKPEELLRVQGALIWNISPLMSSAQPPLMYTTSLWTHPY 775
            .|.:.::..|:|.:.:.|::|||||.|..::|:||.|||:|::..::::.:...:|..|....|.
plant   337 DEFKRVISSLRGHDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVLNTPEVSRVYIGSFSDKPI 401

  Fly   776 QDGAP---ARLLLAQER----AFLRDL-RTAIDKRIEHKIASARRFAVRVRNHAKMVDCYLNTFN 832
            .:.|.   .|.|..:|:    |.|:|: :.|.|:||...:..||  |.::  ||.::.   :...
plant   402 NEAATGPIGRELFEKEQDDLLADLKDIPKKACDRRINEFVKRAR--AAKI--HAYIIS---HLKK 459

  Fly   833 NHKTLFGNKK---RIADDIIDH----PQNYHIYEGLSTLTNISRYDLPDPEVYRDFFRLNPLYEF 890
            ....:.|..|   ::.|::.|.    .:.:|:.:|          |.|:.:.:|:......:.:|
plant   460 EMPAIMGKAKAQQKLIDNLEDEFGKVQREHHLPKG----------DFPNVDHFREVLSGYNIDKF 514

  Fly   891 KKLRDTCTYFRGCPITKLDLAIAYELPELAGKYK 924
            :||:...       :..:|..:.|::|||...:|
plant   515 EKLKPKM-------LQTVDDMLGYDIPELLKNFK 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9297	NP_001262553.1	TSP3 repeat_long	167..205	CDD:275366
		EHD_N	539..569	CDD:293485	9/29 (31%)
		EHD	574..813	CDD:206740	78/249 (31%)
EHD1	NP_001030731.1	EH	19..85	CDD:238009
		EHD_N	163..195	CDD:407121	9/31 (29%)
		EHD	199..443	CDD:206740	76/245 (31%)
		DUF5600	435..537	CDD:407981	23/125 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1954
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D377342at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11216
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920