DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9297 and ehd3

DIOPT Version :9

Sequence 1:	NP_001262553.1	Gene:	CG9297 / 41688	FlyBaseID:	FBgn0038181	Length:	952	Species:	Drosophila melanogaster
Sequence 2:	XP_031757636.1	Gene:	ehd3 / 779678	XenbaseID:	XB-GENE-961795	Length:	551	Species:	Xenopus tropicalis

Alignment Length:	422	Identity:	108/422 - (25%)
Similarity:	199/422 - (47%)	Gaps:	48/422 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   524 REKATDNVAEIILRDIKRIYENAVKPLETLYKYRDLSNRHFSDPEIFSKPLILFMGPWSGGKSSI 588
            |.|....|.:.:...::::|:..:.|||..||:.:..:....|.:..:||::|.:|.:|.||::.
Frog    10 RRKKDPEVFQTVSDGLRKLYKTKLLPLEEYYKFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTF 74

  Fly   589 LNYLTDNEYTPNSLRTGAEPSPAYFNILMWGNETEVLDGTQLAAD--YTFAGLQKFGQGLEERLR 651
            :.||.:.::.  .:|.|.||:...|..:|.|:...|:.|..|..|  ..|..|..||.....|..
Frog    75 IRYLLEQDFP--GMRIGPEPTTDSFIAVMHGDVEGVIPGNALVVDPKKPFRKLNAFGNAFLNRFV 137

  Fly   652 GLKMKSKILEKVNIVEIPGILEVRKQ-VSRV----------------FPFNDACQWFIDRADIIF 699
            ..::.|.:||.:::::.||||...|| :||.                :.|....:||.:|.|.|.
Frog   138 CAQLPSPVLESISVIDTPGILSGEKQRISREREESGYSGLRRCTYGGYDFAAVLEWFAERVDRII 202

  Fly   700 LVYDPAKLDVGPETEAILDQLKGREYQTRIILNKADTVKPEELLRVQGALIWNISPLMSSAQPPL 764
            |::|..|||:..|...::..||..|.:.|::|||||.::.::|:||.|||:|::..::::.:...
Frog   203 LLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIR 267

  Fly   765 MYTTSLWTHPYQDGAPARLLLAQERAFLRDL----RTAIDKRIEHKIASARRFAVRVRNHAKMVD 825
            :|..|.|:||.......:|..|:|:...||:    |.|..:::...|..||...|    ||.::.
Frog   268 VYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKV----HAYIIS 328

  Fly   826 CYLNTFNNHKTLFG---NKKRIADDIIDHPQNYHIYEGLSTLTNISRYDLPDPEVYRDFFRLNPL 887
               :.......:||   .||.:...:.:      ||..:.....||..|.|:.:..:|.......
Frog   329 ---SLKKEMPAVFGKDNKKKELVAGLGE------IYARIEREHQISPGDFPNLKKMQDLLLAQDF 384

  Fly   888 YEFKKLRDTCTYFRGCPITKLDLAIAYELPEL 919
            .:|:.|::..       :..:|..:|:::..|
Frog   385 NKFQPLKNKL-------LETVDEMLAHDIAHL 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9297	NP_001262553.1	TSP3 repeat_long	167..205	CDD:275366
		EHD_N	539..569	CDD:293485	7/29 (24%)
		EHD	574..813	CDD:206740	77/261 (30%)
ehd3	XP_031757636.1	EHD_N	24..56	CDD:407121	7/31 (23%)
		EHD	60..316	CDD:206740	75/257 (29%)
		DUF5600	304..410	CDD:407981	23/126 (18%)
		EH	454..547	CDD:197477
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D377342at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920