DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9297 and ehd2

DIOPT Version :9

Sequence 1:	NP_001262553.1	Gene:	CG9297 / 41688	FlyBaseID:	FBgn0038181	Length:	952	Species:	Drosophila melanogaster
Sequence 2:	NP_001025664.1	Gene:	ehd2 / 595056	XenbaseID:	XB-GENE-957213	Length:	538	Species:	Xenopus tropicalis

Alignment Length:	412	Identity:	114/412 - (27%)
Similarity:	195/412 - (47%)	Gaps:	40/412 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   522 NAREKATDNVAEIILRDIKRIYENAVKPLETLYKYRDLSNRHFSDPEIFSKPLILFMGPWSGGKS 586
            |.:.|.:..|...:...:|.:|:..:||:|..|::.|..:....|.:..:||::|.:|.:|.||:
Frog     8 NEKTKKSPEVIHTVTEGLKDLYKKKLKPVEDFYRFHDFHSPALEDADFDNKPMVLVVGQYSTGKT 72

  Fly   587 SILNYLTDNEYTPNSLRTGAEPSPAYFNILMWGNETEVLDGTQLAAD--YTFAGLQKFGQGLEER 649
            :.:.||.:.: .|.| |.|.||:...|..:|.|....|:.|..|..|  ..|..|..||.....|
Frog    73 TFIKYLLEQD-IPGS-RIGPEPTTDSFIAVMHGETEGVIPGNALMVDPNKPFRKLNPFGNTFLNR 135

  Fly   650 LRGLKMKSKILEKVNIVEIPGILEVRKQ-VSRVFPFNDACQWFIDRADIIFLVYDPAKLDVGPET 713
            .....:.:|:||.:::::.||||...|| |||.:.|....|||.:|.|.|.|::|..||::..|.
Frog   136 FMCAHLPNKVLESISLIDTPGILSGAKQRVSRGYDFPAVLQWFAERVDRIILLFDAHKLEISDEF 200

  Fly   714 EAILDQLKGREYQTRIILNKADTVKPEELLRVQGALIWNISPLMSSAQPPLMYTTSLWTHPYQDG 778
            ...:..|||.|.:.|::|||||.|:.::|:||.|||:|::..:.::.:...:|..|.|:.|....
Frog   201 SEAIRALKGNEDKIRVVLNKADMVETQQLMRVYGALMWSLGKVFNTPEVLRVYIGSFWSEPLMIS 265

  Fly   779 APARLLLAQERAFLRDLRTAIDKRIEHKIASARRFAVRVRNHAKMVDCYLNTFNNHKTLFG--NK 841
            ...||...:|:...:|::.........|:....:.|..||.||.::.   :......::||  ||
Frog   266 DNRRLFELEEQDLFQDIQNLPRNSALRKLNDLVKRARLVRVHAHIIS---HLKKEMPSVFGKDNK 327

  Fly   842 KR---------IADDIIDHPQNYHIYEGLSTLTNISRYDLPDPEVYRDFFRLNPLYEFKKLRDTC 897
            |:         .|...::|    ||..|          |.||....::..   .:::|||.....
Frog   328 KKQLINKLPVIFAKIQLEH----HISPG----------DFPDCAKMQEQL---AIHDFKKFHALK 375

  Fly   898 TYFRGCPITKLDLAIAYELPEL 919
            .:.    |..||..:..::.:|
Frog   376 PHM----IDALDEMLTVDIAKL 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9297	NP_001262553.1	TSP3 repeat_long	167..205	CDD:275366
		EHD_N	539..569	CDD:293485	8/29 (28%)
		EHD	574..813	CDD:206740	76/241 (32%)
ehd2	NP_001025664.1	EHD_N	<35..56	CDD:374864	5/20 (25%)
		EHD	60..300	CDD:206740	76/241 (32%)
		DUF5600	288..394	CDD:375591	26/130 (20%)
		EH	438..531	CDD:197477
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D377342at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920