DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9297 and ehd4

DIOPT Version :9

Sequence 1:	NP_001262553.1	Gene:	CG9297 / 41688	FlyBaseID:	FBgn0038181	Length:	952	Species:	Drosophila melanogaster
Sequence 2:	NP_001373766.1	Gene:	ehd4 / 569546	ZFINID:	ZDB-GENE-060810-22	Length:	546	Species:	Danio rerio

Alignment Length:	366	Identity:	107/366 - (29%)
Similarity:	193/366 - (52%)	Gaps:	22/366 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   517 LDEEFNAREKATDNVAEIILRDIKRIYENAVKPLETLYKYRDLSNRHFSDPEIFSKPLILFMGPW 581
            :::|...|.|..| :.:.:...::.:|...:.|||..|.:.|..:....:.:..|||::|.:|.:
Zfish     5 VNKEQGGRNKEGD-MFQTVTEGLQSLYTKKLLPLEETYLFHDFHSPALEEADFQSKPMVLLVGQY 68

  Fly   582 SGGKSSILNYLTDNEYTPNSLRTGAEPSPAYFNILMWGNETEVLDGTQLAAD--YTFAGLQKFGQ 644
            |.||::.:.||.:.::.  .:|.|.||:...|..:|:.:...|:.|..|..|  ..|..|..||.
Zfish    69 STGKTTFIRYLLEQDFP--GMRIGPEPTTDGFIAVMYNDNEGVVPGNALVVDPKKPFRKLNSFGN 131

  Fly   645 GLEERLRGLKMKSKILEKVNIVEIPGILEVRKQ-VSRVFPFNDACQWFIDRADIIFLVYDPAKLD 708
            ....|....:|.:::|:.::|::.||||...|| :||.:.|::..:||.:|.|.|.|::|..|||
Zfish   132 SFLNRFICSQMPNQVLQSISIIDTPGILSGEKQRISRGYDFSEVLRWFGERVDRIILLFDAHKLD 196

  Fly   709 VGPETEAILDQLKGREYQTRIILNKADTVKPEELLRVQGALIWNISPLMSSAQPPLMYTTSLWTH 773
            :..|....:...:|::.:.|::|||||.|..::|:||.|||:|::..::::.:...:|..|.|..
Zfish   197 ISDEFSEAIRAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVVRVYLGSFWAK 261

  Fly   774 PYQDGAPARLLLAQERAFLRDL----RTAIDKRIEHKIASARRFAVRVRNHAKMVDCYLNTFNNH 834
            |.|:....||..|:.:...||:    |.|..:::...|..||...|    ||.::. ||.  ...
Zfish   262 PLQNAENRRLFEAETQDLFRDIQGLPRNAALRKLNDLIKRARLAKV----HAYIIS-YLK--KEM 319

  Fly   835 KTLFGNKKRIADDIIDH-PQNYHIYEGLSTLTNISRYDLPD 874
            .:|||.:|: .:::|.| |:   ||:.|....:||..|.|:
Zfish   320 PSLFGKEKK-KEELIAHLPE---IYQILQREHHISPGDFPN 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9297	NP_001262553.1	TSP3 repeat_long	167..205	CDD:275366
		EHD_N	539..569	CDD:293485	6/29 (21%)
		EHD	574..813	CDD:206740	75/245 (31%)
ehd4	NP_001373766.1	EHD_N	25..57	CDD:407121	6/31 (19%)
		EHD	61..301	CDD:206740	73/241 (30%)
		DUF5600	289..395	CDD:407981	23/79 (29%)
		EH	439..532	CDD:197477
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1954
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D377342at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910