DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9297 and srl

DIOPT Version :9

Sequence 1:	NP_001262553.1	Gene:	CG9297 / 41688	FlyBaseID:	FBgn0038181	Length:	952	Species:	Drosophila melanogaster
Sequence 2:	NP_001070999.1	Gene:	srl / 449670	ZFINID:	ZDB-GENE-061110-91	Length:	482	Species:	Danio rerio

Alignment Length:	459	Identity:	197/459 - (42%)
Similarity:	288/459 - (62%)	Gaps:	24/459 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   492 EDELLWEGHIPENRRSRQHITELLQLDEEFNAREKATDNVAEIILRDIKRIYENAVKPLETLYKY 556
            |||::.:..:    |.|.||.|.|:|    .|.|||.|..|  .|:.:::||.|:::|:|..|||
Zfish    20 EDEVVLDSIL----RDRSHIEETLRL----AADEKAGDYAA--ALQRLRKIYHNSIRPMEQAYKY 74

  Fly   557 RDLSNRHFS------------DPEIFSKPLILFMGPWSGGKSSILNYLTDNEYTPNSLRTGAEPS 609
            .:|.....|            |.||.|||::||:||||.||||::|||.....||..|.|||||:
Zfish    75 NELRQHEISAYPGRTLGDSATDGEITSKPMVLFLGPWSVGKSSMINYLLGLLDTPYQLYTGAEPT 139

  Fly   610 PAYFNILMWGNETEVLDGTQLAAD--YTFAGLQKFGQGLEERLRGLKMKSKILEKVNIVEIPGIL 672
            .:.|.::|.|.:...::|..:|||  .:|:.|:||||...|:|.|::|...:||:|..|:.|||:
Zfish   140 TSEFTVIMHGEKIRTVEGIVMAADSSRSFSPLEKFGQNFLEKLVGIEMPHSLLERVTFVDTPGII 204

  Fly   673 EVRKQVSRVFPFNDACQWFIDRADIIFLVYDPAKLDVGPETEAILDQLKGREYQTRIILNKADTV 737
            |.|||..|.:||||.|||||||||:||:|:||.|||||.|.|.:..||||||.|.||||||||::
Zfish   205 ENRKQQERGYPFNDVCQWFIDRADLIFVVFDPTKLDVGLELEMLFRQLKGRESQIRIILNKADSL 269

  Fly   738 KPEELLRVQGALIWNISPLMSSAQPPLMYTTSLWTHPYQDGAPARLLLAQERAFLRDLRTAIDKR 802
            ..::|:||.|||.|:::||::..:||.:|.:|.|.:.|.......|...:|.:.|.||...|:.|
Zfish   270 ATQDLMRVYGALFWSLAPLINVTEPPRVYVSSFWPYDYAPDTSRELFKREEISLLEDLNQVIENR 334

  Fly   803 IEHKIASARRFAVRVRNHAKMVDCYLNTFNNHKTLFGNKKRIADDIIDHPQNYHIYEGLSTLTNI 867
            :|:|||..|:..:|||.||.:||.|:.||....:.|.:.:.:..:|:|.|..::|::.:...||:
Zfish   335 LENKIAFIRQHGIRVRIHALLVDRYVQTFKEKMSFFSDPELVFKEIVDDPDKFYIFKSILAKTNV 399

  Fly   868 SRYDLPDPEVYRDFFRLNPLYEFKKLRDTCTYFRGCPITKLDLAIAYELPELAGKYKKMSEAALA 932
            |::|||:.:.|||||.:||:..||:|...|:|..||.:.|::.||.:|||.|.|........||:
Zfish   400 SKFDLPNRDAYRDFFGINPISSFKQLSAQCSYIGGCLLEKIERAITHELPSLLGSINSGKNPALS 464

  Fly   933 AIEA 936
            :.||
Zfish   465 SCEA 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9297	NP_001262553.1	TSP3 repeat_long	167..205	CDD:275366
		EHD_N	539..569	CDD:293485	11/41 (27%)
		EHD	574..813	CDD:206740	117/240 (49%)
srl	NP_001070999.1	EHD_N	56..83	CDD:293485	9/26 (35%)
srl	NP_001070999.1	EHD	104..345	CDD:206740	117/240 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581342
Domainoid	1	1.000	170	1.000	Domainoid score	I3737
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D377342at2759
OrthoFinder	1	1.000	-	-		FOG0006934
OrthoInspector	1	1.000	-	-		otm26524
orthoMCL	1	0.900	-	-		OOG6_109022
Panther	1	1.100	-	-	LDO	PTHR11216
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5026
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.850