DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9297 and Past1

DIOPT Version :9

Sequence 1:	NP_001262553.1	Gene:	CG9297 / 41688	FlyBaseID:	FBgn0038181	Length:	952	Species:	Drosophila melanogaster
Sequence 2:	NP_731737.1	Gene:	Past1 / 41569	FlyBaseID:	FBgn0016693	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	118/382 - (30%)
Similarity:	198/382 - (51%)	Gaps:	25/382 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   519 EEFNAREKATDNVAEIILRDIKRIYENAVKPLETLYKYRDLSNRHFSDPEIFSKPLILFMGPWSG 583
            :.|..|||.|..|.|.::.::|:||.:.:.|||..|::.|..:....||:..:||:||.:|.:|.
  Fly     8 DSFLKREKNTQEVVENVIGELKKIYRSKLLPLEEHYQFHDFHSPKLEDPDFDAKPMILLVGQYST 72

  Fly   584 GKSSILNYLTDNEYTPNSLRTGAEPSPAYFNILMWGNETEVLDGTQLAAD--YTFAGLQKFGQGL 646
            ||::.:.||.:.::.  .:|.|.||:...|..:|:.::..|:.|..|..|  ..|..|.|:|...
  Fly    73 GKTTFIRYLLERDFP--GIRIGPEPTTDRFIAVMYDDKEGVIPGNALVVDPKKQFRPLSKYGNAF 135

  Fly   647 EERLRGLKMKSKILEKVNIVEIPGILEVRKQ-VSRVFPFNDACQWFIDRADIIFLVYDPAKLDVG 710
            ..|.:...:.|.:|..::||:.||||...|| :.|.:.|....:||.:|.|.|.|::|..|||:.
  Fly   136 LNRFQCSSVASPVLNAISIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDIS 200

  Fly   711 PETEAILDQLKGREYQTRIILNKADTVKPEELLRVQGALIWNISPLMSSAQPPLMYTTSLWTHPY 775
            .|....::.|||.:.:.||||||||.:..::|:||.|||:|::..::.:.:...:|..|.|..|.
  Fly   201 DEFRRSIEALKGHDDKIRIILNKADMIDHQQLMRVYGALMWSLGKVLQTPEVARVYIGSFWDQPL 265

  Fly   776 QDGAPARLLLAQERAFLRDL----RTAIDKRIEHKIASARRFAVRVRNHAKMVDCYLNTFNNHKT 836
            :..|..||...:|:...|||    |.|..:::...|..||...|    ||.::   .....:..:
  Fly   266 RFDANRRLFEDEEQDLFRDLQSLPRNAALRKLNDLIKRARLAKV----HAFII---AELRKDMPS 323

  Fly   837 LFGNKKRIADDIIDHPQNYHIYEGLSTLTNISRYDLPD----PEV--YRDFFRLNPL 887
            :||...:..|.|.:..|   :|:.:....:||..|.||    .||  ::||.:.:.|
  Fly   324 VFGKDSKKKDLIKNLGQ---VYDRIQREHSISPGDFPDIKKMQEVLQHQDFTKFHSL 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9297	NP_001262553.1	TSP3 repeat_long	167..205	CDD:275366
		EHD_N	539..569	CDD:293485	10/29 (34%)
		EHD	574..813	CDD:206740	80/245 (33%)
Past1	NP_731737.1	EHD_N	27..59	CDD:407121	10/31 (32%)
		EHD	63..303	CDD:206740	78/241 (32%)
		DUF5600	291..397	CDD:407981	23/97 (24%)
		EH	446..538	CDD:197477
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459012
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1954
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D377342at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11216
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850