DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht5 and Cht9

DIOPT Version :9

Sequence 1:	NP_650314.1	Gene:	Cht5 / 41687	FlyBaseID:	FBgn0038180	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_611543.3	Gene:	Cht9 / 37392	FlyBaseID:	FBgn0034582	Length:	368	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	145/381 - (38%)
Similarity:	209/381 - (54%)	Gaps:	33/381 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLLLGVLCSWPAATVASDQASRIV-CYFSNWAVYRTGIGRYGLEDVPADLCTHIIYSFIGVNDKS 70
            |.||.|||   .:.|..  |.||| ||:..||.||:|.|::.:.::.|.||||:.|||.|:||..
  Fly     5 LALLAVLC---LSQVIG--AERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGINDNG 64

  Fly    71 WDVLVIDPELDVDQGGFSKFTQLKKSNPNVKLEIAVGGWAEGGSKYSQMVAVRDRRQSFIRSVVR 135
             ::..:|..||.|.|..::...||..|.|:|:...||||.||.:|||.|.....:||:||.|.:.
  Fly    65 -EIQSLDTWLDYDLGFINQAISLKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSALN 128

  Fly   136 FMKQYNFDGFDLDWEYPGATDRGGNYGDKDKFLYFVEELRRAFDREGRGWEITMAVPVAKFRLNE 200
            .::.:.|||.|||||||  ..||||:.|:..|:..:.|::.||  ...|:|:.:||...:...:.
  Fly   129 LLRNHGFDGLDLDWEYP--NQRGGNWNDRANFVTLLREIKEAF--APYGYELGIAVGAGESLASA 189

  Fly   201 GYHVPELCEALDAIHAMTYDLRGNWAGFADVHSPLYKRKHDQYAYEKLNVNDGLALWEEMGCPAN 265
            .|.:..:.:.:|.|:.||||......|....::|       |:|     |.:.:..|...|.|||
  Fly   190 SYEIANIAQQVDFINVMTYDFAMASDGQTGFNAP-------QWA-----VENAINFWLSQGAPAN 242

  Fly   266 KLVVGVPFYGRTFTLSNSNKNYNMGTYINKEAGGGAPGPYTNASGFLAYYEICTEVMDKSKGWTV 330
            |||:||..|||:|.||:|::|:.....    .|.|:.|.||.::|:|.|.|||      ...|..
  Fly   243 KLVLGVGTYGRSFQLSDSSQNWPGAPC----RGEGSAGSYTGSTGYLGYNEIC------QNNWHT 297

  Fly   331 EWDDAGMVPYTYKDTQWVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFHGMCG 386
            .:|.....||.|...|||.::|..|:|.||||...:|.||||.|:::.||:.|.||
  Fly   298 VFDYDNAAPYAYSGDQWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQCG 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht5	NP_650314.1	Glyco_18	28..379	CDD:214753	132/351 (38%)
		GH18_chitolectin_chitotriosidase	29..397	CDD:119351	136/359 (38%)
		Trypan_PARP	367..469	CDD:114603	11/20 (55%)
		CBM_14	531..578	CDD:279884
Cht9	NP_611543.3	GH18_chitolectin_chitotriosidase	23..366	CDD:119351	135/358 (38%)
Cht9	NP_611543.3	Glyco_18	23..346	CDD:214753	130/349 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	188	1.000	Domainoid score	I962
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I1632
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	1	1.000	-	-		mtm1002
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	9	8.970