DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht5 and Idgf1

DIOPT Version :9

Sequence 1:	NP_650314.1	Gene:	Cht5 / 41687	FlyBaseID:	FBgn0038180	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_477258.1	Gene:	Idgf1 / 34978	FlyBaseID:	FBgn0020416	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	446	Identity:	112/446 - (25%)
Similarity:	199/446 - (44%)	Gaps:	78/446 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 VRYIPLLLLGVLCSWPAATVASDQASRIVCYFSNWAVYRTGIGRYGLE--DVPADLCTHIIYSFI 64
            :|:....:||:|    :.|..:..||.::||:.:.:..|.|:.:....  |:....|||::|.:.
  Fly     1 MRFQLFYILGLL----SVTSLTHAASNLICYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYA 61

  Fly    65 GVNDKSWDVLVIDPELDVDQGGFSKFTQLKKSNPNVKLEIAVGGWAE----GGSKYSQMV-AVRD 124
            |:  ||..:.:....:|:|...:...|.|::..|.:|:.::|||..:    ..:||.::: |.|.
  Fly    62 GL--KSGTLELFSLNVDLDMFYYKDITALRQKFPQLKILLSVGGDRDVDEAHPNKYVELLEANRT 124

  Fly   125 RRQSFIRSVVRFMKQYNFDGFDLDWEYPGATDRG-----GNY---------GD----------KD 165
            .:|:||.|.:..:|:..|||.||.::.|....|.     |:|         ||          |.
  Fly   125 AQQNFIDSSMILLKRNGFDGLDLAFQLPRNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKS 189

  Fly   166 KFLYFVEELRRAFDREGRGWEITMAVPVAKFRLNEGYH--VPELCEALDAIHAMTYD----LRGN 224
            :|...|..::.||    |...:.:::.|.. .:|..::  ||:|....|.|:...:|    ||.
  Fly   190 QFTDLVGNIKNAF----RSANLMLSLTVLP-NVNSTWYFDVPKLHPQFDYINLAAFDFLTPLRN- 248

  Fly   225 WAGFADVHSPLYKRKHDQYAYEKLNVNDGLALWEEMGCPANKLVVGVPFYGRTFTLSNSNKNYNM 289
             ...||..:|:: .:.:|.....|||...:..|.:..||..||.:|:..|||.:.||..:.  ..
  Fly   249 -PEEADFTAPIF-FQDEQNRLPHLNVEFQINYWLQNHCPGQKLNLGIASYGRAWKLSKGSG--LS 309

  Fly   290 GTYINKEAGGGAPG--PYTNASGFLAYYEICTEV--------------MDKSKGWTVEWDDAGMV 338
            |..|..|..|.|||  ...:|.|.|::.|||:::              :.|....|.::.:..:.
  Fly   310 GAPIVHETCGVAPGGIQIQSAEGLLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKYGNYALR 374

  Fly   339 PYTYKDTQ-----WVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFHGMC-GRK 388
            |   .|..     |:.:::.....||..:.|.:|..|...:.:..|||.|:| |:|
  Fly   375 P---ADDNGDFGVWLSFDDPDFAGIKAVYAKGKGLGGIALFDLSYDDFRGLCTGQK 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht5	NP_650314.1	Glyco_18	28..379	CDD:214753	98/408 (24%)
		GH18_chitolectin_chitotriosidase	29..397	CDD:119351	105/419 (25%)
		Trypan_PARP	367..469	CDD:114603	9/23 (39%)
		CBM_14	531..578	CDD:279884
Idgf1	NP_477258.1	GH18_IDGF	23..438	CDD:119352	105/420 (25%)
Idgf1	NP_477258.1	Glyco_18	24..417	CDD:214753	98/407 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910