DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht5 and Chil6

DIOPT Version :9

Sequence 1:	NP_650314.1	Gene:	Cht5 / 41687	FlyBaseID:	FBgn0038180	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	XP_017175043.1	Gene:	Chil6 / 229688	MGIID:	2682303	Length:	452	Species:	Mus musculus

Alignment Length:	398	Identity:	146/398 - (36%)
Similarity:	212/398 - (53%)	Gaps:	41/398 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ASRIVCYFSNWAVYRTGIGRYGLEDVPADLCTHIIYSFIGVNDKSWD---VLVIDPELDVDQGGF 87
            |.:::|||:||..::..:.....||:...||||:||||.|:    |:   .:....||| |..||
Mouse    38 AYQLMCYFNNWPQHQPDVRDIKHEDIDPCLCTHLIYSFAGI----WENNFTMTKRKELD-DYKGF 97

  Fly    88 S---------KFTQLKKSNPNVKLEIAVGGWAEGGSKYSQMVAVRDRRQSFIRSVVRFMKQYNFD 143
            :         :|......|..:|..:::|.|..|...:..||:..:.|.|||.|:::|:::|.||
Mouse    98 NDLKKRQHLWRFIHASFRNNKLKTLLSIGCWNFGDGSFITMVSTPENRHSFITSIIKFLRKYGFD 162

  Fly   144 GFDLDWEYPGATDRGGNYG----DKDKFLYFVEELRRAFDREGRGWE-----ITMAVPVAKFRLN 199
            |.:|.|:|||.      ||    ||..|...:.|:|:||::|....:     :|.||......:.
Mouse   163 GLNLAWQYPGC------YGSPPRDKHLFTILMHEIRKAFEKEVSKNKKPRLMVTAAVAGVISTIQ 221

  Fly   200 EGYHVPELCEALDAIHAMTYDLRGNWAGFADVHSPLYKRKHDQYAYEKLNVNDGLALWEEMGCPA 264
            .||.:|:|.::||.|..|||||.|:|.|:...:|||||...:.......|:...:..|::.|...
Mouse   222 FGYEIPQLSQSLDYIQVMTYDLHGSWDGYTGENSPLYKSPIETGVKAFHNIKYIMDNWKKKGASP 286

  Fly   265 NKLVVGVPFYGRTFTLSNSNKNYNMGTYINKEAGGGAPGPYTNASGFLAYYEICTEVMDKSKGWT 329
            .||:||.|.||.||.||:|.|. .:|...|:   ||.|||:|..:||.|||||||.:   ..|..
Mouse   287 EKLIVGFPAYGHTFILSDSTKT-EIGAPSNR---GGHPGPHTKQTGFWAYYEICTFL---KNGAI 344

  Fly   330 VEWDDAGMVPYTYKDTQWVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFHG-MCGRKN-GLT 392
            ..|:.|..|||.:...:||||:|..|..||..::|:..|.|||.|.|||||:.| .||:.. .||
Mouse   345 QVWNAAQQVPYAFHGNEWVGYDNIKSFHIKAQWLKRNNYGGAMIWTIDMDDYTGSFCGQGTFPLT 409

  Fly   393 QILYDNMK 400
            .||...:|
Mouse   410 SILKKTLK 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht5	NP_650314.1	Glyco_18	28..379	CDD:214753	134/371 (36%)
		GH18_chitolectin_chitotriosidase	29..397	CDD:119351	144/390 (37%)
		Trypan_PARP	367..469	CDD:114603	18/36 (50%)
		CBM_14	531..578	CDD:279884
Chil6	XP_017175043.1	GH18_chitolectin_chitotriosidase	41..416	CDD:119351	144/392 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920