DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht5 and chil-23

DIOPT Version :9

Sequence 1:	NP_650314.1	Gene:	Cht5 / 41687	FlyBaseID:	FBgn0038180	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_001254212.1	Gene:	chil-23 / 187739	WormBaseID:	WBGene00011167	Length:	432	Species:	Caenorhabditis elegans

Alignment Length:	442	Identity:	100/442 - (22%)
Similarity:	190/442 - (42%)	Gaps:	109/442 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 VRYIPLLLLGV---LCSWPAATVASDQA----SRIVCYFSNWAVYRTGIGRYGLEDVPADLCTHI 59
            :..|.::::|.   ||:.......||..    .||:.|:|       |.|...:........||.
Worm    41 ITLISIIIVGFGLGLCAQIYFQAESDVLPICDKRIIGYYS-------GSGTSNITSTQLSNLTHT 98

  Fly    60 IYSFIGVNDKSWDVLVIDPELDVDQGGFSKFTQLKK----SNPNVKLEIAVGGWAEGGSKY-SQM 119
            :::|:.:....  .|:.:.:::.     ::|.:||:    .|..:||..::||  :..||| |.:
Worm    99 VFAFVYMTPDG--TLLFNNQIEK-----NRFLKLKEVVRNGNSKIKLMFSIGG--KDNSKYFSSV 154

  Fly   120 VAVRDRRQSFIRSVVRFMKQYNFDGFDLDWEYPGATDRGGNYGDKDKFLYFVEELRRAFDREGRG 184
            :...:|.|:||.|::.|::.|:.||.||.|::|....|       |.:..|:.:||:.|:.:.:.
Worm   155 IPSEERIQTFIESILEFLEAYDLDGVDLFWKWPEEEYR-------DAYFAFINQLRKTFEAKKKY 212

  Fly   185 WEITMAVPV------AKFRLNEGYHVPELCEALDAIHAMTYDLRGNWAGFADVHSPLYKRKHDQY 243
            :.:::.:|.      .|.|||      ::.|::|.|:|.:          .|.::||.....|..
Worm   213 YILSIVIPPPTLDGWGKKRLN------KIIESVDFINAYS----------TDYYTPLADNLSDDI 261

  Fly   244 A------------YEKLNVNDGLALWEEMGCPANKLVVGVPFYGRTF-----TLSNSNKNYNMGT 291
            |            ..:.||:.....:..:...|:|..:.:|||...:     |:.:|.:    |.
Worm   262 AGPSAPIYFGAQGKSERNVHHTARNYSCLTKQASKFNIVIPFYATLWENVYETVLDSKR----GV 322

  Fly   292 YINKEAGGGAPGPY---TNASGFLAYYEICTEVMDKSKGWTVE---WDDAGMVPYTYKDT--QWV 348
            |.:       ..|:   |....:|:...:      |.:|:.||   :|.|....::|..|  .::
Worm   323 YRH-------VAPFYGRTVGKTYLSRLAV------KQEGFQVESYSYDPAPRAAFSYNRTIGIYL 374

  Fly   349 GYENEASIQIKMDFIKQRGYAGAMTWAIDMDD----------FHGMCGRKNG 390
            .:|.:.||:.|:|::|.|...|...:::||||          |.|.|...||
Worm   375 TFETKESIRAKIDYVKDRILGGVWIFSVDMDDETNSQLKAVSFDGFCTIGNG 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht5	NP_650314.1	Glyco_18	28..379	CDD:214753	86/386 (22%)
		GH18_chitolectin_chitotriosidase	29..397	CDD:119351	93/408 (23%)
		Trypan_PARP	367..469	CDD:114603	10/34 (29%)
		CBM_14	531..578	CDD:279884
chil-23	NP_001254212.1	Glyco_18	74..405	CDD:214753	86/386 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1289629at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920