DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht5 and chil-22

DIOPT Version :9

Sequence 1:	NP_650314.1	Gene:	Cht5 / 41687	FlyBaseID:	FBgn0038180	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_496031.2	Gene:	chil-22 / 187738	WormBaseID:	WBGene00011166	Length:	450	Species:	Caenorhabditis elegans

Alignment Length:	354	Identity:	82/354 - (23%)
Similarity:	156/354 - (44%)	Gaps:	53/354 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 THIIYSFIGVNDKSWDVLVIDPELDVDQGGFSKFTQL-KKSNPNVKLEIAVGGWAEGGSKYSQMV 120
            ||.:::|: :......|:..|   .:.|..|.|...: .:::|.:|:.|::||.| ....:..::
Worm   104 THAVFAFV-IMKSDGTVMFRD---KLAQERFLKIRDIANQASPKLKMLISIGGPA-NSDNFLPVI 163

  Fly   121 AVRDRRQSFIRSVVRFMKQYNFDGFDLDWEYPGATDRGGNYGDKDKFLY--FVEELRRAFDREGR 183
            :..||::.||.|:|.|:|:|:.||.||.|::|..         :||:.|  |:..|:..|..|.:
Worm   164 SSPDRKKIFINSIVSFLKKYDIDGVDLFWKWPRL---------EDKYYYSRFISMLKERFQMEEK 219

  Fly   184 GWEITMAVPVAKF-RLNEGYHVPELCEALDAIHAMTYDLRGNW----AGFADVHSPLYKRKHDQY 243
            .:.:::.:|...| ..|..:.:..:....|.|:..:.|..|.|    .......||:|.....:.
Worm   220 NYILSIIIPPCGFGGWNNKFDIENIVAVADFINIYSMDYYGPWKNPYGNPTGPISPIYNGAQGRE 284

  Fly   244 AYEKLNVNDGLALWEEMGCPANKLVVGVPFYGRTF-TLSNSNKNYNMGTYINKE-AGGGAPGPYT 306
            ||   ||:.....:......:.|..:.:||:.|.: .:....::.....|.|.. ..|.|.|
Worm   285 AY---NVHSSALTYSCKVKQSKKFNIVIPFFARLWKNVEKPIQHPGREVYRNVHLVHGSAVG--- 343

  Fly   307 NASGFLAYYEICTEVMDKSKGW---TVEWDDAGMVPYTYKDT--QWVGYENEASIQIKMDFIKQR 366
              ..|::...:.      .||:   :..:|:.....:.|..|  :::.:|.|.||:.|::::|.|
Worm   344 --ESFMSRKSVL------EKGYKLNSYSYDELSRSAFIYNSTTKEYLTFETEKSIEAKVNYVKDR 400

  Fly   367 GYAGAMTWAIDMDD----------FHGMC 385
            ..||...|.:|:||          |.|:|
Worm   401 ALAGVWIWFVDLDDEENSLINAVNFTGLC 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht5	NP_650314.1	Glyco_18	28..379	CDD:214753	77/336 (23%)
		GH18_chitolectin_chitotriosidase	29..397	CDD:119351	82/354 (23%)
		Trypan_PARP	367..469	CDD:114603	9/29 (31%)
		CBM_14	531..578	CDD:279884
chil-22	NP_496031.2	Glyco_18	82..413	CDD:214753	77/336 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810