DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht5 and chil-11

DIOPT Version :9

Sequence 1:	NP_650314.1	Gene:	Cht5 / 41687	FlyBaseID:	FBgn0038180	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_500856.2	Gene:	chil-11 / 183470	WormBaseID:	WBGene00016665	Length:	389	Species:	Caenorhabditis elegans

Alignment Length:	394	Identity:	91/394 - (23%)
Similarity:	158/394 - (40%)	Gaps:	95/394 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DQASRIVCYF---SNWAVYRTGIGRYGLEDVPADLCTHIIYSFIGVNDKSWDVLVIDPELDVDQG 85
            |...||:.|:   .:..:...|:.|          .||.::..:.|.        ::...::. .
Worm     9 DVIKRIIGYYIQKESSEISTVGLSR----------LTHAVFGSLRVQ--------LNGTFEIG-N 54

  Fly    86 GFS--KFTQ----LKKSNPNVKLEIAVGGWAEGGSKYSQMVAVRDRRQSFIRSVVRFMKQYNFDG 144
            .||  ||..    :|.|:.|||..|::|.|.......|.::.|:.||. ||.|:|.|:|::..||
Worm    55 AFSKRKFKNWQRAVKNSSSNVKSMISIGRWDSVTQLSSVLLNVKSRRM-FIESIVDFLKEHQLDG 118

  Fly   145 FDLDWEY-PGATDRGGNYGDKDKFLYFVEELRRAFDREGRGWEITM-AVPVAKFRLNEGYHVPEL 207
            .||.|.: |.|.        :.:|..|:||::..|..:.:.:.::: |.||......:||.:.|:
Worm   119 IDLFWRWVPLAV--------QSEFCLFLEEVKIEFLNQEKQYILSITAPPVGIENYEDGYDIEEI 175

  Fly   208 CEALD--AIHAMTY--DLRGNWAGFADVHSPLYKRKHDQYAYEKLNVNDGLALWEEMGCPANKLV 268
            .|.:|  .:::|.|  .....|.......:|||....   |..|.:|:..:..:........|..
Worm   176 IERVDFVNVYSMNYAAPWSNQWGTPTGPSAPLYGGLD---ARRKFSVDYTMKYYIRYTRKPEKFN 237

  Fly   269 VGVPFYGRTF-TLSNSNKNYNMGTYINKEAGGGAPGPYTNASGFLAYYEICTEVMDKSKG----- 327
            :.:|||.|.: .:.|:.|                ||           .|:...|..::.|
Worm   238 LIIPFYVRHWRNVENAIK----------------PG-----------IEVFRNVTLQNNGAIGEV 275

  Fly   328 ----WTVE----------WDDAGMVPYTYK-DTQ-WVGYENEASIQIKMDFIKQRGYAGAMTWAI 376
                ||.|          |||.....|.:| :|: ::.:|.|.||:.|.:::|.....|...|.:
Worm   276 YMSRWTAESDGIELSNPSWDDTTKTLYIWKPETKTFITFETEKSIEAKANYVKSMNLGGVWIWLM 340

  Fly   377 DMDD 380
            :.||
Worm   341 ENDD 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht5	NP_650314.1	Glyco_18	28..379	CDD:214753	88/387 (23%)
		GH18_chitolectin_chitotriosidase	29..397	CDD:119351	89/389 (23%)
		Trypan_PARP	367..469	CDD:114603	4/14 (29%)
		CBM_14	531..578	CDD:279884
chil-11	NP_500856.2	Glyco_18	13..343	CDD:214753	88/387 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810