DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht5 and chil-8

DIOPT Version :9

Sequence 1:	NP_650314.1	Gene:	Cht5 / 41687	FlyBaseID:	FBgn0038180	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_001379090.1	Gene:	chil-8 / 174541	WormBaseID:	WBGene00007473	Length:	399	Species:	Caenorhabditis elegans

Alignment Length:	449	Identity:	109/449 - (24%)
Similarity:	186/449 - (41%)	Gaps:	122/449 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YIPLLLLGVLCSWPAATVASDQASRIVCYFSNWA--------VYRTGIGRYGLEDVPADL----- 55
            ::.|.:.|::         |...|.:.|||.:::        ::|..|..|...|..:::
Worm    12 FVLLFVFGIV---------SFLVSSLFCYFYDFSNSVQSPSVLHRKRIIGYVSSDEGSEITIKQL 67

  Fly    56 --CTHIIYSFIGVNDKSWDVLVIDPELDVDQGGFSKFTQLKKS----NPNVKLEIAVGGWAEGGS 114
              .||:|::||.|:.        |..:....|....|..:|:.    |..:|:.:::||: |...
Worm    68 EKLTHVIFAFILVHK--------DGTIKFKYGTKDGFFDMKRKSMELNRGLKVMVSIGGY-ESSP 123

  Fly   115 KYSQMVAVRDRRQSFIRSVVRFMKQYNFDGFDLDWEYPGATDRGGNYGDKDKFLYFVEELRRAF- 178
            .:|.::.  .:::..|.|:...:|:::.||.|:.|.:|..||: .||      |.|:.|||:..
Worm   124 LFSDVLV--KKKKKLIASIALLVKKFDLDGVDIFWNWPSITDQ-SNY------LIFIRELRKKLT 179

  Fly   179 ---DREGRGWE--ITMAVPVAKFRLNEGYHVPELCEALDAIHAMTYD--LRGNWAGFADVHSPLY 236
               |..||..|  |::..|.:.......|...|:.|.:|.|:.:|::  ...|..|   .|||||
Worm   180 NLKDENGRSNEYVISVIAPSSSSHSEYPYKWTEILENVDFINVITFEYFYEANKIG---PHSPLY 241

  Fly   237 KRKHDQYAYEKLNVNDGLALWEEMGC---PANKLVVGVPF----YGRTFTLSNSNKNYNMGTYIN 294
            .....       ||:|.|   :.:.|   ..|||.:.|.|    :|.| ||...:|    |.:|.
Worm   242 GGSFG-------NVDDTL---KYLICRTRTPNKLNMVVSFNGIYWGNT-TLPFDDK----GVWIP 291

  Fly   295 KEAGGGAPGPYTNASGFLAYYEICTEVMDKSKGW-------------TVEWDDAGMVPYTYK-DT 345
            .::   |.|||                   |.||             ..||::....||.:| ||
Worm   292 DDS---AQGPY-------------------SYGWKQFARMSHGFDQNDFEWNEETRTPYIWKADT 334

  Fly   346 -QWVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFHGMCGRKNGLTQILYDNMKNYR 403
             |::.:|||.|:..||::.......|...:.||.||      .:|.|..::..|:.:.:
Worm   335 QQFLTFENEKSLTEKMNYAVAHNIGGVAMYTIDDDD------EENTLLNVVVTNLPSLK 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht5	NP_650314.1	Glyco_18	28..379	CDD:214753	100/399 (25%)
		GH18_chitolectin_chitotriosidase	29..397	CDD:119351	104/416 (25%)
		Trypan_PARP	367..469	CDD:114603	8/37 (22%)
		CBM_14	531..578	CDD:279884
chil-8	NP_001379090.1	Glyco_18	49..369	CDD:214753	96/377 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1289629at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820