DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht5 and chil-13

DIOPT Version :9

Sequence 1:	NP_650314.1	Gene:	Cht5 / 41687	FlyBaseID:	FBgn0038180	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_496018.2	Gene:	chil-13 / 174500	WormBaseID:	WBGene00010945	Length:	439	Species:	Caenorhabditis elegans

Alignment Length:	399	Identity:	95/399 - (23%)
Similarity:	163/399 - (40%)	Gaps:	97/399 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 RIVCYFSNWAVYRTGIGRYGLEDVPADLCTHIIYSFIGVNDKSWDVLVIDPELDVDQGGFS-KFT 91
            |||.|||.  :..|.|.:..:     |..||.:::|:.:.        .|..|..|..... :|:
Worm    81 RIVGYFSE--IESTEISKSQI-----DKLTHAVFAFVRIK--------YDGTLQFDNSKADLRFS 130

  Fly    92 QLKKS--NPNVKLEIAVGGWAEGGSKYSQMVAVRDRRQSFIRSVVRFMKQYNFDGFDLDWEYPGA 154
            .||..  ..||::.:::||..|....::..::...::::||.|::.|:.::..||.|..|::|..
Worm   131 ILKDKTRGSNVEMMVSIGGGYENAHYFASALSDSQKKKNFIDSILAFLVEHRIDGVDFFWQWPTV 195

  Fly   155 TDRGGNYGDKDKFLY--FVEELRRAFDREGR-GWEITMAVPVA---KFRLNEGYHVPELCEALDA 213
                     :|.|.|  |:.|||:..|...| .:.|:|.||.|   .:.|  |:.:.||...:|.
Worm   196 ---------QDTFNYVTFIRELRQKLDENKRKHFLISMTVPAAGVDNWEL--GFDLEELQNHVDF 249

  Fly   214 IHAMTYDLRGNWAGFADV----HSPLYKRKHDQYAYEKLNVNDGLALW--EEMGCPANK---LVV 269
            .:..:.|..|.|.....|    .||::   ::..|.:...|:     |  :...|...:   |.:
Worm   250 FNVYSMDYAGPWPNQWGVPTGPSSPMF---YNIGARKNFYVD-----WTMKHYTCKLKQPSMLNM 306

  Fly   270 GVPFYGRTF-----TLSNSNKNYNMGTYINKEAGGGAPGPYTNASGFLAYYEICTEVMDKSKGWT 329
            .:||..|.:     .:.|..:.:......|..|.|.                  |::    ..||
Worm   307 VIPFSARIWNNVQEAIDNRTEVFRNAELKNNMAEGR------------------TQI----SRWT 349

  Fly   330 VE----------WDDAGMVPY--TYKDTQWVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFH 382
            .|          ||:..|.||  ..|...::.:|::.||:||.|:.|:....|...|::||||
Worm   350 AEHEGLELSPSSWDNLTMTPYILDLKAKTFLTFEDKRSIKIKTDYAKKMDLGGVWLWSVDMDD-- 412

  Fly   383 GMCGRKNGL 391
                |.|.|
Worm   413 ----RLNSL 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht5	NP_650314.1	Glyco_18	28..379	CDD:214753	89/385 (23%)
		GH18_chitolectin_chitotriosidase	29..397	CDD:119351	94/398 (24%)
		Trypan_PARP	367..469	CDD:114603	9/25 (36%)
		CBM_14	531..578	CDD:279884
chil-13	NP_496018.2	Glyco_18	81..411	CDD:214753	89/385 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820