DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht5 and chil-24

DIOPT Version :9

Sequence 1:	NP_650314.1	Gene:	Cht5 / 41687	FlyBaseID:	FBgn0038180	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_494455.1	Gene:	chil-24 / 173661	WormBaseID:	WBGene00020407	Length:	410	Species:	Caenorhabditis elegans

Alignment Length:	383	Identity:	89/383 - (23%)
Similarity:	166/383 - (43%)	Gaps:	85/383 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SRIVCYFSNWAVYRTGIGRYGLEDVPADLCTHIIYSFIGVNDKSWDVLVIDPELDVDQGGFS--- 88
            ||||.::::|.  ||.|..:.:..:     ||.:::::.:.        .|..|     ||.
Worm    54 SRIVGFYADWE--RTDITSHQVAKL-----THAVFAYVQMK--------FDGSL-----GFKNDA 98

  Fly    89 ---KFTQL-----KKSNPNVKLEIAVGGWAEGGSKYSQMVAVRDRRQSFIRSVVRFMKQYNFDGF 145
               :|:.|     :..:.|||:.|::||: |....:..:::..:.:::|:.|:..|:..:...|.
Worm    99 ARIRFSNLRDKVRRNEDSNVKMMISIGGF-ENSQHFYPVLSNVEMKKAFLNSISSFLAYHELHGV 162

  Fly   146 DLDWEYPGATDRGGNYGDKDKFLYFVEELRRAFDREGRGWE--ITMAVPVAKF-RLNEGYHVPEL 207
            |:.|::|...       ||..:..|:.:||:..     |:|  |::|||.|:. .|..||.:..:
Worm   163 DIFWKWPSPE-------DKAHYSRFLADLRQHL-----GYEFIISVAVPQAEVSNLELGYDLRTI 215

  Fly   208 CEALD--AIHAMTY--DLRGNWAGFADVHSPLY-KRKHDQYAYEKLNVNDGLALWEEMGCPANKL 267
            ...:|  .:|:|.|  .....|.......|||| ..:|        ||:..|..:.|......||
Worm   216 SSHVDFFNVHSMDYYGPWPNEWGKPTGPISPLYGPTRH--------NVDWTLRYYAEKTGEPGKL 272

  Fly   268 VVGVPFYGRTFTLSNSNKNYNMGTYI--------NKEAGGGAPGPYTNASGFLAYYEICTEVMDK 324
            .:.:||:.|.:  .|..:....|..:        ||..|          ..:::.:....|.:|.
Worm   273 NMVIPFFVRLW--KNVPEPVEPGRQVFRDVELVDNKPQG----------EAYMSRWSAQHEELDL 325

  Fly   325 SKGWTVEWDDAGMVPYTYK-DTQ-WVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDD 380
            |   ..:||:.....||:. ||: :|.:|.:.|||.||.::|::...|...|.:|.::
Worm   326 S---PADWDEETRSSYTWNPDTRNFVTFETDKSIQEKMKYVKEKNLGGVWIWHVDANE 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht5	NP_650314.1	Glyco_18	28..379	CDD:214753	88/379 (23%)
		GH18_chitolectin_chitotriosidase	29..397	CDD:119351	87/381 (23%)
		Trypan_PARP	367..469	CDD:114603	3/14 (21%)
		CBM_14	531..578	CDD:279884
chil-24	NP_494455.1	Glyco_18	55..378	CDD:214753	87/378 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1289629at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820