DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Adgf-C and AMD1

DIOPT Version :9

Sequence 1:	NP_650308.3	Gene:	Adgf-C / 41680	FlyBaseID:	FBgn0038173	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_013677.1	Gene:	AMD1 / 854973	SGDID:	S000004498	Length:	810	Species:	Saccharomyces cerevisiae

Alignment Length:	410	Identity:	88/410 - (21%)
Similarity:	136/410 - (33%)	Gaps:	144/410 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 HVHNTASVSSKWVVDDLSYMPGLLRCTTATGQSILSFRRTPKEHKCQSQYV------LVSDERRN 166
            |||::|.::.|                     .:|.|.:....|....:.:      |..||...
Yeast   362 HVHHSACMNQK---------------------HLLRFIKHKLRHSKDEKVIFRDGKLLTLDEVFR 405

  Fly   167 SLDRQVYDRNFERL--------------INL-YTPVPELEYPTITRVWDRFQGMFDGLSDAL--I 214
            ||....||.:.:.|              .|| |.|:.|          .|.:.:|...::.:  .
Yeast   406 SLHLTGYDLSIDTLDMHAHKDTFHRFDKFNLKYNPIGE----------SRLREIFLKTNNYIKGT 460

  Fly   215 YLPAFRAYHWQMLEELYNDNVMYTEIRTSFKTLYDASGRTFPRERTIHELYALNQKFMKLHPDFL 279
            ||.....   |::.:|.|......|.|.|   :|   ||:.             .::.||....:
Yeast   461 YLADITK---QVIFDLENSKYQNCEYRIS---VY---GRSL-------------DEWDKLASWVI 503

  Fly   280 GFKVI-------MAVYRGYELDHLKDIVEVFK---------------------KLHQALPHFLVG 316
            ..|||       :.:.|.|::.....||:.|:                     |||..|.. ::|
Yeast   504 DNKVISHNVRWLVQIPRLYDIYKKTGIVQSFQDICKNLFQPLFEVTKNPQSHPKLHVFLQR-VIG 567

  Fly   317 FDLVGQEDK---------GKP-----------------LYSLLPVLRDLPP-----TARLFLHGG 350
            ||.|..|.|         .||                 |||.:..|.....     |..|..|.|
Yeast   568 FDSVDDESKVDRRFHRKYPKPSLWEAPQNPPYSYYLYYLYSNVASLNQWRAKRGFNTLVLRPHCG 632

  Fly   351 ETNWFGASTDINLLDALLMNTTRIGHGYALAKHPILLNAVKSRRIAVELSPISNQVLHLVWDLRN 415
            |     |....:|:.|.|: ...|.||..|.|.|.:.......::.:.:||:||..|.|.:|  .
Yeast   633 E-----AGDPEHLVSAYLL-AHGISHGILLRKVPFVQYLYYLDQVGIAMSPLSNNALFLTYD--K 689

  Fly   416 HPGSQFFALDVPVVICNDDP 435
            :|..::|...:.|.:..|||
Yeast   690 NPFPRYFKRGLNVSLSTDDP 709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-C	NP_650308.3	A_deaminase_N	5..98	CDD:285627
		adm_rel	25..501	CDD:273620	88/410 (21%)
		ADGF	78..493	CDD:238646	88/410 (21%)
AMD1	NP_013677.1	AMPD	299..794	CDD:238644	88/410 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900