Protein Alignment Adgf-C and AMPD3

DIOPT Version :9

• Sequence 1: NP_650308.3
• Gene: Adgf-C / 41680
• FlyBaseID: FBgn0038173
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_000471.1
• Gene: AMPD3 / 272
• HGNCID: 470
• Length: 776
• Species: Homo sapiens
• Alignment Length: 576
• Identity: 126/576 - (21%)
• Similarity: 196/576 - (34%)
• Gaps: 186/576 - (32%)

  Fly     5 LMFVVLLTAQLQIQAQTALSYEQARQAVLTAEE--ELMTGG------HTHLNTEEEKVDDIFMEY 61
            ::||......|:.|...:|.|.......:....  .|:|.|      |..||..|.|..   :..
Human   237 ILFVYDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFS---LHE 298

  Fly    62 KLGELAQGFRNAEQNAAALHFFKAKPLIDRSAIFRFLQKMPKGSVLHVHNTASVSSKWVVDDLSY 126
            .|.|::: |:.          .|:.|..|    |..::|:.    .|:|..|.::.|
Human   299 MLNEMSE-FKE----------LKSNPHRD----FYNVRKVD----THIHAAACMNQK-------- 336

  Fly   127 MPGLLRCTTATGQSILSFRRTPKEHKCQ-------------SQYVLVSDERRNSLD----RQVYD 174
              .|||....|.|:  ...||..|.:.:             ..|.|..|    |||    ||.:.
Human   337 --HLLRFIKHTYQT--EPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVD----SLDVHAGRQTFH 393

  Fly   175 RNFERLINLYTPVPELEYPTITRVWDRFQGMFDGLSDALIYLPAFRAYHWQMLE----ELYNDNV 235
            | |::..:.|.||...|...:....:.:.|               ..|..:|::    ||.....
Human   394 R-FDKFNSKYNPVGASELRDLYLKTENYLG---------------GEYFARMVKEVARELEESKY 442

  Fly   236 MYTEIRTSFKTLYDASGRTFPRER---TIHELYALNQKFMKLHPDFLGFKVIMAVYRGYELDHLK 297
            .|:|.|.|   :|..|...:|...   ..|::|:.|.::            |:.|.|.|::...|
Human   443 QYSEPRLS---IYGRSPEEWPNLAYWFIQHKVYSPNMRW------------IIQVPRIYDIFRSK 492

  Fly   298 DIVEVFKKL-----------------HQALPHFL---VGFDLVGQEDKGKP-------------- 328
            .::..|.|:                 |:.|..||   .|||.|..|.|...
Human   493 KLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWT 557

  Fly   329 -------------LYSLLPVLRDLPPTARL--FL---HGGETNWFGASTDINLLDALLMNTTRIG 375
                         :|:.:.||.:|.....|  ||   |.||     |.:..:|:.|.| ....|.
Human   558 SEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGE-----AGSITHLVSAFL-TADNIS 616

  Fly   376 HGYALAKHPILLNAVKSRRIAVELSPISNQVLHLVWDLRNHPGSQFFALDVPVVICNDDPGFWNA 440
            ||..|.|.|:|.......:|.:.:||:||..|.|  :...:|..:|....:.|.:..|||
Human   617 HGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFL--EYSKNPLREFLHKGLHVSLSTDDP----- 674

  Fly   441 KGLSYDFYYAIMSLAPNNAGLRLLKTLVW------------NSVRYSTLTEEEQTR 484
                ..|:|...:|....|    :...||            |||..|.|:.:|:.:
Human   675 ----MQFHYTKEALMEEYA----IAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQK 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-C	NP_650308.3	A_deaminase_N	5..98	CDD:285627	21/100 (21%)
		adm_rel	25..501	CDD:273620	121/556 (22%)
		ADGF	78..493	CDD:238646	109/495 (22%)
AMPD3	NP_000471.1	AMP_deaminase	155..762	CDD:273618	126/576 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900