Protein Alignment Adgf-C and Ampd1

DIOPT Version :9

• Sequence 1: NP_650308.3
• Gene: Adgf-C / 41680
• FlyBaseID: FBgn0038173
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001028475.2
• Gene: Ampd1 / 229665
• MGIID: 88015
• Length: 745
• Species: Mus musculus
• Alignment Length: 568
• Identity: 118/568 - (20%)
• Similarity: 194/568 - (34%)
• Gaps: 204/568 - (35%)

  Fly     7 FVVLLTAQLQIQAQTALSYEQARQAVLTAEEELMTGGHTHLNTEEEKVDDIFMEYKLGELA---- 67
            |::.|.||..::     :|...|...|:::.::    |..||..:|          |.||.
Mouse   244 FLLALIAQGPVK-----TYAHRRLKFLSSKFQV----HQMLNEMDE----------LKELKNNPH 289

  Fly    68 QGFRNAEQNAAALHFFKAKPLIDRSAIFRFLQK---MPKGSVLHVHNTASVSSKWVVDDLSYMPG 129
            :.|.|..:....:|   |...:::..:.||::|   :....|::.....|::.|.:...|:..|
Mouse   290 RDFYNCRKVDTHIH---AAACMNQKHLLRFIKKSYHIDADRVVYSTKEKSLTLKELFAKLNMHP- 350

  Fly   130 LLRCTTATGQSILSFRRTPKEHKCQSQYVLVSDERRNSLD----RQVYDRNFERLINLYTPVPEL 190
                                       |.|..|    |||    ||.:.| |::..:.|.||
Mouse   351 ---------------------------YDLTVD----SLDVHAGRQTFQR-FDKFNDKYNPV--- 380

  Fly   191 EYPTITRVWDRFQGMFDGLSDALIYLPAFRAYHWQMLEELY--NDNVMYTEIRTSFKTLYDASGR 253
                             |.|:               |.:||  .||.:..|.   |.|:....|.
Mouse   381 -----------------GASE---------------LRDLYLKTDNYINGEY---FATIIKEVGA 410

  Fly   254 TFPRERTIH-----ELYALN-QKFMKLHPDFLGFKV-------IMAVYRGYELDHLKDIVEVFKK 305
            .....:..|     .:|..: .::.||...|:..::       ::.|.|.|::...|:.:..|.|
Mouse   411 DLVEAKYQHAEPRLSIYGRSPDEWNKLSSWFVCNRIYCPNMTWMIQVPRIYDVFRSKNFLPHFGK 475

  Fly   306 L-----------------HQALPHFL---VGFDLVGQEDK----------GKP------------ 328
            :                 |..|..||   .|||.|..|.|          .||
Mouse   476 MLENIFLPVFEATINPQAHPDLSVFLKHITGFDSVDDESKHSGHMFSSKSPKPEEWTMENNPSYT 540

  Fly   329 -----LYSLLPVLRDLPPTARL--FL---HGGETNWFGASTDINLLDALLMNTTRIGHGYALAKH 383
                 :|:.:.||..|.....:  ||   |.||.   ||.|  :|:.|.:: ...|.||..|.|.
Mouse   541 YYAYYMYANITVLNSLRKERGMNTFLFRPHCGEA---GALT--HLMTAFMI-ADNISHGLNLKKS 599

  Fly   384 PILLNAVKSRRIAVELSPISNQVLHLVWDLRNHPGSQFFALDVPVVICNDDPGFWNAKGLSYDF- 447
            |:|.......:|.:.:||:||..|.|  :...:|...|....:.:.:..|||       :.:.|
Mouse   600 PVLQYLFFLAQIPIAMSPLSNNSLFL--EYAKNPFLDFLQKGLMISLSTDDP-------MQFHFT 655

  Fly   448 ------YYAIMSLAPNNAGLRLLKT-----LVWNSVRYSTLTEEEQTR 484
                  .|||.      |.:..|.|     :..|||....::.||:.:
Mouse   656 KEPLMEEYAIA------AQVFKLSTCDMCEVARNSVLQCGISHEEKAK 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-C	NP_650308.3	A_deaminase_N	5..98	CDD:285627	19/94 (20%)
		adm_rel	25..501	CDD:273620	114/550 (21%)
		ADGF	78..493	CDD:238646	102/493 (21%)
Ampd1	NP_001028475.2	PLN03055	129..740	CDD:178613	118/568 (21%)
		AMPD	238..734	CDD:238644	118/568 (21%)
		Substrate binding. /evidence=ECO:0000250	372..377		0/4 (0%)
		Substrate binding. /evidence=ECO:0000250	648..651		2/9 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900