DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adgf-C and Ada

DIOPT Version :9

Sequence 1:	NP_650308.3	Gene:	Adgf-C / 41680	FlyBaseID:	FBgn0038173	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_001258981.1	Gene:	Ada / 11486	MGIID:	87916	Length:	352	Species:	Mus musculus

Alignment Length:	331	Identity:	71/331 - (21%)
Similarity:	122/331 - (36%)	Gaps:	60/331 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 ERLINLYTPVPELEYPTITRVWDRFQGMFDGLSDALIYLPAFRAYHWQMLEELYNDNVMYTEIRT 242
            |.|.|:......|..|.....:|.:..:..|..:|:      :...::.:|....:.|:|.|:|.
Mouse    44 EELRNIIGMDKPLSLPGFLAKFDYYMPVIAGCREAI------KRIAYEFVEMKAKEGVVYVEVRY 102

  Fly   243 SFKTLYDASGRTFPRERTIHELY------ALNQKFMKLHPDFLGFKV--IMAVYRGYELDHLKDI 299
            |...|.::.....|..:|..::.      .:||...:....| |.||  |:...| ::.....::
Mouse   103 SPHLLANSKVDPMPWNQTEGDVTPDDVVDLVNQGLQEGEQAF-GIKVRSILCCMR-HQPSWSLEV 165

  Fly   300 VEVFKKLHQALPHFLVGFDLVGQED-KGKPLYSLLP---------VLRDLPPTARLFLHGGETNW 354
            :|:.||.:|..   :|..||.|.|. :|.   ||.|         |...:..|    :|.||.
Mouse   166 LELCKKYNQKT---VVAMDLAGDETIEGS---SLFPGHVEAYEGAVKNGIHRT----VHAGEV-- 218

  Fly   355 FGASTDINLLDALLMNTTRIGHGYALAKHPILLNAVKSRRIAVELSPISN--------QVLHLVW 411
              .|.::......::.|.|:||||...:...|.|.:....:..|:.|.|:        :..|.|.
Mouse   219 --GSPEVVREAVDILKTERVGHGYHTIEDEALYNRLLKENMHFEVCPWSSYLTGAWDPKTTHAVV 281

  Fly   412 DLRNHPGSQFFALDVPVVICNDDPGFWNAKGLSYDFYYAIMSLAPNNAGLRLLKTLVWNSVRYST 476
            ..:|...:.....|.|::       |.:.....|......|......     .|.|..|:.:.|.
Mouse   282 RFKNDKANYSLNTDDPLI-------FKSTLDTDYQMTKKDMGFTEEE-----FKRLNINAAKSSF 334

  Fly   477 LTEEEQ 482
            |.|||:
Mouse   335 LPEEEK 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-C	NP_650308.3	A_deaminase_N	5..98	CDD:285627
		adm_rel	25..501	CDD:273620	71/331 (21%)
		ADGF	78..493	CDD:238646	71/331 (21%)
Ada	NP_001258981.1	ADA	8..336	CDD:238645	67/325 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810