Protein Alignment Adgf-D and ampd3a

DIOPT Version :10

• Sequence 1: NP_524345.2
• Gene: Adgf-D / 41679
• FlyBaseID: FBgn0038172
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_009301872.2
• Gene: ampd3a / 556578
• ZFINID: ZDB-GENE-110407-2
• Length: 787
• Species: Danio rerio
• Alignment Length: 543
• Identity: 109/543 - (20%)
• Similarity: 182/543 - (33%)
• Gaps: 179/543 - (32%)

  Fly    54 EKANSILMNAKR------------------AEIAEGLKTPEK-YAPAMHFFQGRQY-----VRQS 94
            |.|.::.||..|                  |.||:|   |.| |......|.|.::     :.:.
Zfish   255 ENAEALSMNKPRCLPYPDLETFAIDMSHVLAMIADG---PTKTYCHRRLNFLGSKFYLHEMLNEM 316

  Fly    95 EVFRMIQKIPKGAFLHGHNTGMVTSRWIIQNLTTTNNLYTCRNVDGLLVFTYDQSGCHSEVQNVC 159
            ...:.::.:|...|.:            ::.:.|..:...|.|...||.|.  |:...::.:.|.
Zfish   317 AELKELKGVPHRDFYN------------VRKVDTHIHAAACMNQKHLLDFI--QTTYKTDAERVV 367

  Fly   160 TER----------INAEDRGKYERQLEKHINMHGPRPEALLPNRKKIWERFENIFTTVDRLYKYR 214
            .|:          .|..:...|:..::. :::|..|         :.:.||:...:      ||.
Zfish   368 LEKAGLKLTLKQVFNNLNMDPYDLTVDS-LDVHAGR---------QTFHRFDKFNS------KYN 416

  Fly   215 PTYCAYHKRMLEELCEDNIIYAEIRASLSPLYDDNNRTLSTLEVANELE---------------R 264
            |...:..:.:.  |..||.|..|..|.|            ..|||:.||               |
Zfish   417 PVGASELREIY--LKADNYINGEYFARL------------IKEVAHNLEESKYQHAEPRLSIYGR 467

  Fly   265 IVEEFKAKHHDFIGVKV----------------IYAKRNRASE-EEMLRRI-------TTFKQLH 305
            ..||:::..|.||..||                |:..|..... .:||..:       |...|.|
Zfish   468 SPEEWESLSHWFIQNKVYSPNMRWIIQVPRIYDIFRSRKLVPNFAKMLENVFLPLFEATVNPQKH 532

  Fly   306 ---HAKPNFVIGFDLIGQE--------------------DTGEPLNRY-------INQLSDLP-- 338
               |....:|.|||.:..|                    |...|.:.|       |..|::|.
Zfish   533 KELHVFLKYVTGFDSVDDESKHSDHMFSYKSPKPEQWTTDDNPPYSYYLFHMYANIMVLNNLRKE 597

  Fly   339 ---STANYFFHAGETNWNGRTDWNMMDAILLNTKRIGHAFALPKHPQLWSTIKKRNIAIEVNPIS 400
               ||..:..|.||..    :..:::.| .|....|.|...|.|.|.|........:.|.::|:|
Zfish   598 RGLSTFQFRPHCGEAG----SITHLVSA-FLTADNISHGLNLKKSPVLQYLYYLAQVPIAMSPLS 657

  Fly   401 NQVLGFVWDLRNHPASFLIAENFPIVISSDDPGVWGAKGLSYDFYY---AFMALAPADADLRFLK 462
            |..| |: :...:|....:.:...:.:|:|||         ..|:|   |.|......|.|..|.
Zfish   658 NNSL-FL-EYSKNPLREFLHKGLCVSLSTDDP---------MQFHYTKEALMEEYAIAAQLWKLS 711

  Fly   463 -----QLALNSIKYAVLTSDERR 480
                 ::|.||:..:.|:.:|::
Zfish   712 TCDVCEIARNSVLQSGLSHEEKK 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-D	NP_524345.2	A_deaminase_N	4..100	CDD:462481	14/69 (20%)
		ADGF	80..490	CDD:238646	97/498 (19%)
ampd3a	XP_009301872.2	AMP_deaminase	149..781	CDD:437158	109/543 (20%)