Protein Alignment Adgf-D and ampd3b

DIOPT Version :10

• Sequence 1: NP_524345.2
• Gene: Adgf-D / 41679
• FlyBaseID: FBgn0038172
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_956142.1
• Gene: ampd3b / 333997
• ZFINID: ZDB-GENE-030131-5929
• Length: 779
• Species: Danio rerio
• Alignment Length: 558
• Identity: 106/558 - (18%)
• Similarity: 179/558 - (32%)
• Gaps: 194/558 - (34%)

  Fly    45 GNIWLSSDEEKANSILMNAKRAEIAEGLKTP--EKYAPAMHFFQGRQYVRQSEVFRMIQKIPKGA 107
            |.|::..:|:        |.:.::...|..|  |.:|           :..|.|..||...|...
Zfish   239 GIIYVYDNED--------ALKQDLPRSLPYPDLETFA-----------IDLSHVLAMIADGPTKT 284

  Fly   108 FLHGHNTGMVTSRWIIQNLTTT------------NNLYTCRNVD------------GLLVFTYDQ 148
            :.| .....:||::.:..:...            .:.|..|.||            .||.|..|.
Zfish   285 YCH-RRLNFLTSKFQLHEMLNEMAELKELKCVPHRDFYNVRKVDTHIHAAACMNQKHLLKFIQDS 348

  Fly   149 SGCHSEVQNVCTERINAEDRGK---------------YERQLEKHINMHGPRPEALLPNRKKIWE 198
            ....:       :|:..|..||               |:..::. :::|..|         :.:.
Zfish   349 YQTEA-------DRVVLEKGGKKFTLKQVFENLKMDPYDLTVDS-LDVHAGR---------QTFH 396

  Fly   199 RFENIFTTVDRLYKYRPTYC----------------AYHKRMLEELCED----NIIYAEIRASLS 243
            ||:...:      ||.|...                .|..|:::|:..|    ...:||.|.|:.
Zfish   397 RFDKFNS------KYNPVGANELREIYLKTDNYINGEYFARLIKEVAHDLEESKYQHAEPRLSIY 455

  Fly   244 PLYDDNNRTLSTLEVANELE-----------RIVEEFKAKHHDFIGVKVIYAKRNRASEEEMLRR 297
            ....:...:||...:..:|.           ||.:.|::|       |:|      |:..:||..
Zfish   456 GRAPEEWESLSKWFIMQKLHSPNMRWMIQVPRIYDIFRSK-------KII------ANFAKMLEN 507

  Fly   298 I-------TTFKQLH---HAKPNFVIGFDLIGQED-----------------TGE---PLNRY-- 330
            |       |...|.|   |.....|.||:.:..|.                 |.|   |...|
Zfish   508 IFLPLFQATVNPQKHKEMHVFLKHVTGFNSVDDESKHSDHIFNYKSPKPEEWTSEENPPYTYYLF 572

  Fly   331 --------INQLSDLPSTANYFF--HAGETNWNGRTDWNMMDAILLNTKRIGHAFALPKHPQLWS 385
                    :|.|........:.|  |.||..    :..:::.| .|....|.|...|.|.|.|..
Zfish   573 HMYANIMVLNNLRKERGLNTFLFRPHCGEAG----SITHLVSA-FLTADNISHGLNLKKSPVLQY 632

  Fly   386 TIKKRNIAIEVNPISNQVLGFVWDLRNHPASFLIAENFPIVISSDDPGVWGAKGLSYDFYY---A 447
            ......:.|.::|:||..| |: :...:|....:.:...:.:|:|||         ..|:|   |
Zfish   633 LYYLAQVPIAMSPLSNNSL-FL-EYSKNPLREFLQKGLCVSLSTDDP---------LQFHYTKEA 686

  Fly   448 FMALAPADADLRFLK-----QLALNSIKYAVLTSDERR 480
            .|......|.|..|.     ::|.||:..:.|:..|::
Zfish   687 LMEEYAIAAQLWKLSTCDTCEIARNSVLQSGLSHQEKK 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-D	NP_524345.2	A_deaminase_N	4..100	CDD:462481	10/56 (18%)
		ADGF	80..490	CDD:238646	98/521 (19%)
ampd3b	NP_956142.1	AMP_deaminase	139..771	CDD:437158	106/558 (19%)