Protein Alignment Adgf-D and AMPD2

DIOPT Version :9

• Sequence 1: NP_524345.2
• Gene: Adgf-D / 41679
• FlyBaseID: FBgn0038172
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001355738.1
• Gene: AMPD2 / 271
• HGNCID: 469
• Length: 825
• Species: Homo sapiens
• Alignment Length: 489
• Identity: 103/489 - (21%)
• Similarity: 168/489 - (34%)
• Gaps: 148/489 - (30%)

  Fly    24 DLPYETLREQIMEAERVASL--GGNI---------WLSSDEEKANSILMNAKRAEIAEGLKTPEK 77
            :|||..|:|.:.:...:.:|  .|.|         :|||..:.  .:|:|..: |:|...|.|.:
Human   292 ELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQM--HVLLNEMK-ELAAQKKVPHR 353

  Fly    78 YAPAMHFFQGRQY---------VRQSEVFRMIQKIPK---GAFLHGHNTGMVTSRWIIQNLTTTN 130
                 .|:..|:.         :.|..:.|.|::..|   ...:|.......|.|.:.:::..|
Human   354 -----DFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLT- 412

  Fly   131 NLYTCRNVDGLLVFTYDQSGCHSEVQNVCTERINAEDRGKYERQLEKHINMHGPRPEALLPNRKK 195
                          .||.|        |.|..::| ||..:.| .:|....:.|..|::|
Human   413 --------------AYDLS--------VDTLDVHA-DRNTFHR-FDKFNAKYNPIGESVL----- 448

  Fly   196 IWERFENIFTTVDRLY--KYRPTYCAYHKRMLEELCEDNIIYAEIRASLSPLYDDNNRTLSTLEV 258
                 ..||...|...  ||   :....|.::.:|.|.....||:|.|:.....|....|:...|
Human   449 -----REIFIKTDNRVSGKY---FAHIIKEVMSDLEESKYQNAELRLSIYGRSRDEWDKLARWAV 505

  Fly   259 AN-----------ELERIVEEFKAKHHDFIGVKVIYAKRNRASEEEMLRRI-------TTFKQLH 305
            .:           ::.|:.:.::             .|...|:.:|||..|       |.....|
Human   506 MHRVHSPNVRWLVQVPRLFDVYR-------------TKGQLANFQEMLENIFLPLFEATVHPASH 557

  Fly   306 ---HAKPNFVIGFDLIGQEDTGEPLNRYINQLSDLPST---------ANYFF------------- 345
               |.....|.|||.:  :|..:|.|...|..|.||..         |.|.:
Human   558 PELHLFLEHVDGFDSV--DDESKPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLR 620

  Fly   346 ------------HAGETNWNGRTDWNMMDAILLNTKRIGHAFALPKHPQLWSTIKKRNIAIEVNP 398
                        |.||..    ...:::.|.:| .:.|.|...|.|.|.|........|.|.::|
Human   621 RQRGFHTFVLRPHCGEAG----PIHHLVSAFML-AENISHGLLLRKAPVLQYLYYLAQIGIAMSP 680

  Fly   399 ISNQVLGFVWDLRNHPASFLIAENFPIVISSDDP 432
            :||..| |:...|| |....::....:.:|:|||
Human   681 LSNNSL-FLSYHRN-PLPEYLSRGLMVSLSTDDP 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-D	NP_524345.2	A_deaminase_N	4..100	CDD:285627	21/95 (22%)
		adm_rel	27..498	CDD:273620	101/486 (21%)
		ADGF	80..490	CDD:238646	86/422 (20%)
AMPD2	NP_001355738.1	AMPD	301..797	CDD:238644	98/480 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810