Protein Alignment Adgf-D and Ampd3

DIOPT Version :9

• Sequence 1: NP_524345.2
• Gene: Adgf-D / 41679
• FlyBaseID: FBgn0038172
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001359370.1
• Gene: Ampd3 / 11717
• MGIID: 1096344
• Length: 775
• Species: Mus musculus
• Alignment Length: 573
• Identity: 110/573 - (19%)
• Similarity: 189/573 - (32%)
• Gaps: 221/573 - (38%)

  Fly    25 LPYETLREQIMEAERVASLGGNIWLSSDEEKANSILMNAKRAEIAEGLKTPEK-YA-PAMHFFQG 87
            |||..|...|::...:.:|                        |.:|   |.| |. ..::|.:.
Mouse   254 LPYPDLETYIVDMSHILAL------------------------ITDG---PTKTYCHRRLNFLES 291

  Fly    88 R----QYVRQSEVFRMIQKIPKGAFLHGHNTGMVTSRWIIQNLTTTNNLYTCRNVDGLLVF---T 145
            :    :.:.:...|:.::..|...|.:            ::.:.|..:...|.|...||.|   |
Mouse   292 KFSLHEMLNEMSEFKELKSNPHRDFYN------------VRKVDTHIHAAACMNQKHLLRFIKHT 344

  Fly   146 YDQSGCHSEVQNVCTERINAEDRGK---------------YERQLEKHINMHGPRPEALLPNRKK 195
            |...          .:|..||..|:               |:..::. :::|..|         :
Mouse   345 YQTE----------PDRTVAEKLGRKITLRQVFDSLHMDPYDLTVDS-LDVHAGR---------Q 389

  Fly   196 IWERFENIFTTVDRLYKYRPTYCA----------------YHKRMLEELC---EDN-IIYAEIRA 240
            .:.||:...:      ||.|...:                |..||::|:.   ||: ..|:|.|.
Mouse   390 TFHRFDKFNS------KYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEDSKYQYSEPRL 448

  Fly   241 SL---SP--------------LYDDNNRTLSTLEVANELERIVEEFKAKHHDFIGVKVI--YAKR 286
            |:   ||              :|..|.|.:.      ::.||.:.|::|       |::  :.|
Mouse   449 SIYGRSPKEWSSLARWFIQHKVYSPNMRWII------QVPRIYDIFRSK-------KLLPNFGK- 499

  Fly   287 NRASEEEMLRRI-------TTFKQLH---HAKPNFVIGFDLIGQED-----------------TG 324
                   ||..|       |...|.|   |....:|.|||.:..|.                 |.
Mouse   500 -------MLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPSPDLWTS 557

  Fly   325 E---PLNRY----------INQLSDLPSTANYFF--HAGETNWNGRTDWNMMDAILLNTKRIGHA 374
            |   |.:.|          :|.|......:.:.|  |.||..    :..:::.| .|....|.|.
Mouse   558 EQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAG----SITHLVSA-FLTADNISHG 617

  Fly   375 FALPKHPQLWSTIKKRNIAIEVNPISNQVLGFVWDLRNHPASFLIAENFPIVISSDDPGVWGAKG 439
            ..|.|.|.|........|.|.::|:||..| |: :...:|....:.:...:.:|:|||
Mouse   618 LLLKKSPVLQYLYYLAQIPIAMSPLSNNSL-FL-EYSKNPLREFLHKGLHVSLSTDDP------- 673

  Fly   440 LSYDFYYAFMALAP-----------ADADLRFLKQLALNSIKYAVLTSDERRK 481
              ..|:|...||..           :..|   |.::|.||:..:.|:..|::|
Mouse   674 --MQFHYTKEALMEEYAIAAQVWKLSTCD---LCEIARNSVLQSGLSHQEKQK 721

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-D	NP_524345.2	A_deaminase_N	4..100	CDD:285627	13/80 (16%)
		adm_rel	27..498	CDD:273620	108/571 (19%)
		ADGF	80..490	CDD:238646	99/516 (19%)
Ampd3	NP_001359370.1	AMP_deaminase	155..761	CDD:273618	110/573 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810