DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ninaB and CCD8

DIOPT Version :9

Sequence 1:	NP_650307.2	Gene:	ninaB / 41678	FlyBaseID:	FBgn0002937	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	NP_001329787.1	Gene:	CCD8 / 829417	AraportID:	AT4G32810	Length:	596	Species:	Arabidopsis thaliana

Alignment Length:	649	Identity:	151/649 - (23%)
Similarity:	248/649 - (38%)	Gaps:	178/649 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PQAERLDGNGRLYPNCSSDVWLRSCEREIVDPIEGHHSGHIPKWICGSLLRNGPGSWKVGDMTFG 89
            |:.|:::|..|.:...:| |...:.|.|:.      ..|.||.|:.|:.||||||.|.:||..|.
plant    68 PEKEKVEGERRCHVAWTS-VQQENWEGELT------VQGKIPTWLNGTYLRNGPGLWNIGDHDFR 125

  Fly    90 HLFDCSALLHRFAIRNGRVTYQNRFVDTETLRKNRSAQRIVVTEFGTAAVPDPCHSIFDR--FAA 152
            ||||..:.|.:.....||:...:|.::::..:..:...|:...||...    |...|.::  |:.
plant   126 HLFDGYSTLVKLQFDGGRIFAAHRLLESDAYKAAKKHNRLCYREFSET----PKSVIINKNPFSG 186

  Fly   153 I------FRPDSGTDNSMISIYPFGD-QYYTFTETP-----FMHRINPCTLATEARICTTDFVGV 205
            |      |..:|.|||:...:...|| :....|||.     ..|.    ||.|..:....|.:.
plant   187 IGEIVRLFSGESLTDNANTGVIKLGDGRVMCLTETQKGSILVDHE----TLETIGKFEYDDVLS- 246

  Fly   206 VNH---TSHPHVLPSGTVYNLGTTMTRSGPAYTILSFPHGEQMFEDAHVVATLPCR---WKLHPG 264
             :|   ::|| ::....::.|...:.:  |.|.::....|....|   ||..:.||   |  .||
plant   247 -DHMIQSAHP-IVTETEMWTLIPDLVK--PGYRVVRMEAGSNKRE---VVGRVRCRSGSW--GPG 302

  Fly   265 YMHTFGLTDHYFVIVEQPLSVSLTEYIKAQLGGQNLSACLKWFEDRPTLFHLIDRVSGKLVQTYE 329
            ::|:|.:|::|.||.|.||..|:...::|:   .......:|........|::.:::|::|.:.|
plant   303 WVHSFAVTENYVVIPEMPLRYSVKNLLRAE---PTPLYKFEWCPQDGAFIHVMSKLTGEVVASVE 364

  Fly   330 SEAFFYLHIINCFERDGH-------VVVDICSYR-NPEMINCMYLEAIANMQTNPNYATLFRGRP 386
            ..|:...|.||.:|.|.:       ::.|.|.:. :..:::.:.|:   .::::..:..|...|.
plant   365 VPAYVTFHFINAYEEDKNGDGKATVIIADCCEHNADTRILDMLRLD---TLRSSHGHDVLPDARI 426

  Fly   387 LRFVLPLGTIPPASIAKRGLVKSFSLAGLSAPQVSRTMKHSVSQYADITYMPTNGKQATAGEESP 451
            .||.:||                                 ..|:|         ||..||.|..
plant   427 GRFRIPL---------------------------------DGSKY---------GKLETAVEAE- 448

  Fly   452 KRDAKRGRYEEENLVNLVTMEGSQAEAFQGTNGIQLRPEMLCDWGCETPRIYYERYMGKNYRYFY 516
                |.||..:...:|.:                                     |:|:.|||.|
plant   449 ----KHGRAMDMCSINPL-------------------------------------YLGQKYRYVY 472

  Fly   517 AISSDVDAVNPGTLIK--------------------------VDVWNKSCLTWCEENVYPSEPIF 555
            |..:......|..|.|                          ||:..|....|.|..:.||||.|
plant   473 ACGAQRPCNFPNALSKVTYIPQTIGFQYSIVLNEPFDNCMRQVDIVEKKVKNWHEHGMIPSEPFF 537

  Fly   556 VPSPDPKSEDDGVILA--SMVLGGLNDRYVGLIVLCAKTMTELGRCDFHTNGPVPKCLHGWFAP 617
            ||.|....|||||:::  |...||     ...|:|...:..|:.|..|...  :|..|||.:.|
plant   538 VPRPGATHEDDGVVISIVSEENGG-----SFAILLDGSSFEEIARAKFPYG--LPYGLHGCWIP 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaB	NP_650307.2	RPE65	52..617	CDD:281102	143/620 (23%)
CCD8	NP_001329787.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	169	1.000	Domainoid score	I1173
eggNOG	1	0.900	-	-		E1_COG3670
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I1540
OMA	1	1.010	-	-		QHG59724
OrthoDB	1	1.010	-	-		D895046at2759
OrthoFinder	1	1.000	-	-		FOG0000856
OrthoInspector	1	1.000	-	-		oto2931
orthoMCL	1	0.900	-	-		OOG6_100941
Panther	1	1.100	-	-	LDO	PTHR10543
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X319
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840